Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5471
MIM: 172450
HGNC: 9238
Ensembl: ENSG00000128059
Variants:
dbSNP: 5471
ClinVar: 5471
TCGA: ENSG00000128059
COSMIC: PPAT
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000128059 | ENST00000264220 | Q06203 |
| ENSG00000128059 | ENST00000264220 | A8K4H7 |
| ENSG00000128059 | ENST00000507724 | D6RE15 |
| ENSG00000128059 | ENST00000510643 | D6RCC8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35798250 | 2022 | SHMT2 promotes the tumorigenesis of renal cell carcinoma by regulating the m6A modification of PPAT. | 6 |
| 35798250 | 2022 | SHMT2 promotes the tumorigenesis of renal cell carcinoma by regulating the m6A modification of PPAT. | 6 |
| 33271445 | 2021 | Phosphopantetheine Adenylyltransferase: A promising drug target to combat antibiotic resistance. | 3 |
| 33785613 | 2021 | Species-Specific Deamidation of RIG-I Reveals Collaborative Action between Viral and Cellular Deamidases in HSV-1 Lytic Replication. | 10 |
| 33271445 | 2021 | Phosphopantetheine Adenylyltransferase: A promising drug target to combat antibiotic resistance. | 3 |
| 33785613 | 2021 | Species-Specific Deamidation of RIG-I Reveals Collaborative Action between Viral and Cellular Deamidases in HSV-1 Lytic Replication. | 10 |
| 27468871 | 2016 | Frameshift mutations of OGDH, PPAT and PCCA genes in gastric and colorectal cancers. | 11 |
| 27468871 | 2016 | Frameshift mutations of OGDH, PPAT and PCCA genes in gastric and colorectal cancers. | 11 |
| 26140362 | 2015 | Role and regulation of coordinately expressed de novo purine biosynthetic enzymes PPAT and PAICS in lung cancer. | 53 |
| 26140362 | 2015 | Role and regulation of coordinately expressed de novo purine biosynthetic enzymes PPAT and PAICS in lung cancer. | 53 |
Citation
Dessen P
PPAT (phosphoribosyl pyrophosphate amidotransferase)
Atlas Genet Cytogenet Oncol Haematol. 2016-08-01
Online version: http://atlasgeneticsoncology.org/gene/55909/gene-explorer/meetings/new-content/
