CELA1 (chymotrypsin like elastase 1)

2016-10-01 Affiliation

Identity

HGNC

CELA1

LOCATION

12q13.13

LOCUSID

1990

ALIAS

ELA1

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 1990
MIM: 130120
HGNC: 3308
Ensembl: ENSG00000139610

Variants:

dbSNP: 1990
ClinVar: 1990
TCGA: ENSG00000139610
COSMIC: CELA1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000139610	ENST00000293636	Q9UNI1

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
29521945	2018	Fecal Elastase Fails to Detect Steatorrhea in Patients With Locally Advanced Pancreatic Cancer.	5
30054822	2018	Serum Elastase 1 Level as a Risk Factor for Postoperative Recurrence in Patients with Well-Differentiated Pancreatic Neuroendocrine Neoplasms.	2
29521945	2018	Fecal Elastase Fails to Detect Steatorrhea in Patients With Locally Advanced Pancreatic Cancer.	5
30054822	2018	Serum Elastase 1 Level as a Risk Factor for Postoperative Recurrence in Patients with Well-Differentiated Pancreatic Neuroendocrine Neoplasms.	2
28604957	2017	[Molecular genetic study of a family affected with punctate palmoplantar keratoderma].	0
28604957	2017	[Molecular genetic study of a family affected with punctate palmoplantar keratoderma].	0
26601880	2015	Inverse association of HbA1c with faecal elastase 1 in people without diabetes.	1
26601880	2015	Inverse association of HbA1c with faecal elastase 1 in people without diabetes.	1
24622077	2014	Nutritional status, fecal elastase-1, and 13C-labeled mixed triglyceride breath test in the long-term after pancreaticoduodenectomy.	3
24949484	2014	NGS nominated CELA1, HSPG2, and KCNK5 as candidate genes for predisposition to Balkan endemic nephropathy.	14
25319362	2014	Extract of the mycelium of T. matsutake inhibits elastase activity and TPA-induced MMP-1 expression in human fibroblasts.	13
24622077	2014	Nutritional status, fecal elastase-1, and 13C-labeled mixed triglyceride breath test in the long-term after pancreaticoduodenectomy.	3
24949484	2014	NGS nominated CELA1, HSPG2, and KCNK5 as candidate genes for predisposition to Balkan endemic nephropathy.	14
25319362	2014	Extract of the mycelium of T. matsutake inhibits elastase activity and TPA-induced MMP-1 expression in human fibroblasts.	13
23395568	2013	Fecal elastase-1 is useful in the detection of steatorrhea in patients with pancreatic diseases but not after pancreatic resection.	19

Citation

Dessen P

CELA1 (chymotrypsin like elastase 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/55958/gene-fusions-explorer/js/welcome