Identity
HGNC
LOCATION
3p11.2
LOCUSID
ALIAS
ALS17,CHMP2.5,DMT1,FTDALS7,VPS2-2,VPS2B
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 25978
MIM: 609512
HGNC: 24537
Ensembl: ENSG00000083937
Variants:
dbSNP: 25978
ClinVar: 25978
TCGA: ENSG00000083937
COSMIC: CHMP2B
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38740816 | 2024 | Methylation of ESCRT-III components regulates the timing of cytokinetic abscission. | 0 |
| 38740816 | 2024 | Methylation of ESCRT-III components regulates the timing of cytokinetic abscission. | 0 |
| 34997757 | 2022 | Six generations of CHMP2B-mediated Frontotemporal Dementia: Clinical features, predictive testing, progression, and survival. | 4 |
| 36414997 | 2022 | The enhanced association between mutant CHMP2B and spastin is a novel pathological link between frontotemporal dementia and hereditary spastic paraplegias. | 2 |
| 34997757 | 2022 | Six generations of CHMP2B-mediated Frontotemporal Dementia: Clinical features, predictive testing, progression, and survival. | 4 |
| 36414997 | 2022 | The enhanced association between mutant CHMP2B and spastin is a novel pathological link between frontotemporal dementia and hereditary spastic paraplegias. | 2 |
| 33583303 | 2021 | Differential levels of CHMP2B, LLPH, and SLC25A51 proteins in secondary renal amyloidosis. | 0 |
| 33832485 | 2021 | The ESCRT-III isoforms CHMP2A and CHMP2B display different effects on membranes upon polymerization. | 14 |
| 34281622 | 2021 | The ESCRT-III protein VPS4, but not CHMP4B or CHMP2B, is pathologically increased in familial and sporadic ALS neuronal nuclei. | 10 |
| 34678206 | 2021 | Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3. | 17 |
| 33583303 | 2021 | Differential levels of CHMP2B, LLPH, and SLC25A51 proteins in secondary renal amyloidosis. | 0 |
| 33832485 | 2021 | The ESCRT-III isoforms CHMP2A and CHMP2B display different effects on membranes upon polymerization. | 14 |
| 34281622 | 2021 | The ESCRT-III protein VPS4, but not CHMP4B or CHMP2B, is pathologically increased in familial and sporadic ALS neuronal nuclei. | 10 |
| 34678206 | 2021 | Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3. | 17 |
| 31587468 | 2020 | Expression of a human variant of CHMP2B linked to neurodegeneration in Drosophila external sensory organs leads to cell fate transformations associated with increased Notch activity. | 2 |
Citation
Dessen P
CHMP2B (charged multivesicular body protein 2B)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/55963/chromosome-explorer/submit-meetings/
