UCN2 (urocortin 2)

2016-10-01  

Identity

HGNC
LOCATION
3p21.31
LOCUSID
ALIAS
SRP,UCN-II,UCNI,UR,URP
FUSION GENES

Other Information

Locus ID:

NCBI: 90226
MIM: 605902
HGNC: 18414
Ensembl: ENSG00000145040

Variants:

dbSNP: 90226
ClinVar: 90226
TCGA: ENSG00000145040
COSMIC: UCN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000145040ENST00000273610Q96RP3

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class B/2 (Secretin family receptors)REACTOMER-HSA-373080

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
319257092020Evaluation of Serum Urocortin 2 Levels in Patients with Hypertension.2
319257092020Evaluation of Serum Urocortin 2 Levels in Patients with Hypertension.2
314430942019Urocortin 2 in patients with hypertension treated with angiotensin converting enzyme inhibitors or angiotensin receptor blockers.1
314430942019Urocortin 2 in patients with hypertension treated with angiotensin converting enzyme inhibitors or angiotensin receptor blockers.1
294996552018Identification of novel enriched recurrent chimeric COL7A1-UCN2 in human laryngeal cancer samples using deep sequencing.5
294996552018Identification of novel enriched recurrent chimeric COL7A1-UCN2 in human laryngeal cancer samples using deep sequencing.5
285501602017Corticotropin releasing hormone receptor 2 exacerbates chronic cardiac dysfunction.15
285501602017Corticotropin releasing hormone receptor 2 exacerbates chronic cardiac dysfunction.15
272758432016Cardiovascular effects of urocortin 2 and urocortin 3 in patients with chronic heart failure.19
272758432016Cardiovascular effects of urocortin 2 and urocortin 3 in patients with chronic heart failure.19
254268722015Urocortin 2 role in placental and myometrial inflammatory mechanisms at parturition.4
261682762015TAS1R3 and UCN2 Transcript Levels in Blood Cells Are Associated With Sugary and Fatty Food Consumption in Children.8
254268722015Urocortin 2 role in placental and myometrial inflammatory mechanisms at parturition.4
261682762015TAS1R3 and UCN2 Transcript Levels in Blood Cells Are Associated With Sugary and Fatty Food Consumption in Children.8
241072262014Urocortin 2 is associated with abdominal aortic aneurysm and mediates anti-proliferative effects on vascular smooth muscle cells via corticotrophin releasing factor receptor 2.10

Citation

Dessen P

UCN2 (urocortin 2)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/55968/ucn2-(urocortin-2)