Identity
HGNC
LOCATION
11q13.5
LOCUSID
ALIAS
APHC,PHCA,PLDECO
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55331
MIM: 617036
HGNC: 16066
Ensembl: ENSG00000078124
Variants:
dbSNP: 55331
ClinVar: 55331
TCGA: ENSG00000078124
COSMIC: ACER3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34817752 | 2022 | LINC01087 indicates a poor prognosis of glioma patients with preoperative MRI. | 4 |
| 35034572 | 2022 | Circular RNA circ_0001955 promotes hepatocellular carcinoma tumorigenesis by up-regulating alkaline ceramidase 3 expression through microRNA-655-3p. | 2 |
| 36048828 | 2022 | Alkaline ceramidase catalyzes the hydrolysis of ceramides via a catalytic mechanism shared by Zn2+-dependent amidases. | 1 |
| 34817752 | 2022 | LINC01087 indicates a poor prognosis of glioma patients with preoperative MRI. | 4 |
| 35034572 | 2022 | Circular RNA circ_0001955 promotes hepatocellular carcinoma tumorigenesis by up-regulating alkaline ceramidase 3 expression through microRNA-655-3p. | 2 |
| 36048828 | 2022 | Alkaline ceramidase catalyzes the hydrolysis of ceramides via a catalytic mechanism shared by Zn2+-dependent amidases. | 1 |
| 34281620 | 2021 | ACER3-related leukoencephalopathy: expanding the clinical and imaging findings spectrum due to novel variants. | 0 |
| 34281620 | 2021 | ACER3-related leukoencephalopathy: expanding the clinical and imaging findings spectrum due to novel variants. | 0 |
| 30097213 | 2018 | Alkaline ceramidase 3 promotes growth of hepatocellular carcinoma cells via regulating S1P/S1PR2/PI3K/AKT signaling. | 19 |
| 30097213 | 2018 | Alkaline ceramidase 3 promotes growth of hepatocellular carcinoma cells via regulating S1P/S1PR2/PI3K/AKT signaling. | 19 |
| 26792856 | 2016 | Deficiency of the alkaline ceramidase ACER3 manifests in early childhood by progressive leukodystrophy. | 24 |
| 27470583 | 2016 | ACER3 supports development of acute myeloid leukemia. | 18 |
| 26792856 | 2016 | Deficiency of the alkaline ceramidase ACER3 manifests in early childhood by progressive leukodystrophy. | 24 |
| 27470583 | 2016 | ACER3 supports development of acute myeloid leukemia. | 18 |
| 20068046 | 2010 | Alkaline ceramidase 3 (ACER3) hydrolyzes unsaturated long-chain ceramides, and its down-regulation inhibits both cell proliferation and apoptosis. | 47 |
Citation
Dessen P
ACER3 (alkaline ceramidase 3)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/55981/acer3-(alkaline-ceramidase-3)
