Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3141
MIM: 609018
HGNC: 4976
Ensembl: ENSG00000159267
Variants:
dbSNP: 3141
ClinVar: 3141
TCGA: ENSG00000159267
COSMIC: HLCS
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37997490 | 2024 | Biotin protein ligase as you like it: Either extraordinarily specific or promiscuous protein biotinylation. | 0 |
| 38493427 | 2024 | CircRNA HLCS regulates lens epithelial cell apoptosis via miR-338-3p/BPNT1 axis. | 0 |
| 37997490 | 2024 | Biotin protein ligase as you like it: Either extraordinarily specific or promiscuous protein biotinylation. | 0 |
| 38493427 | 2024 | CircRNA HLCS regulates lens epithelial cell apoptosis via miR-338-3p/BPNT1 axis. | 0 |
| 36890565 | 2023 | Clinical, biochemical, and genetic analysis of 28 Chinese patients with holocarboxylase synthetase deficiency. | 2 |
| 36890565 | 2023 | Clinical, biochemical, and genetic analysis of 28 Chinese patients with holocarboxylase synthetase deficiency. | 2 |
| 28564555 | 2017 | Holocarboxylase Synthetase: A Moonlighting Transcriptional Coregulator of Gene Expression and a Cytosolic Regulator of Biotin Utilization. | 7 |
| 28564555 | 2017 | Holocarboxylase Synthetase: A Moonlighting Transcriptional Coregulator of Gene Expression and a Cytosolic Regulator of Biotin Utilization. | 7 |
| 24239178 | 2014 | Holocarboxylase synthetase acts as a biotin-independent transcriptional repressor interacting with HDAC1, HDAC2 and HDAC7. | 3 |
| 24840043 | 2014 | Holocarboxylase synthetase interacts physically with nuclear receptor co-repressor, histone deacetylase 1 and a novel splicing variant of histone deacetylase 1 to repress repeats. | 4 |
| 24239178 | 2014 | Holocarboxylase synthetase acts as a biotin-independent transcriptional repressor interacting with HDAC1, HDAC2 and HDAC7. | 3 |
| 24840043 | 2014 | Holocarboxylase synthetase interacts physically with nuclear receptor co-repressor, histone deacetylase 1 and a novel splicing variant of histone deacetylase 1 to repress repeats. | 4 |
| 23624957 | 2013 | Holocarboxylase synthetase synergizes with methyl CpG binding protein 2 and DNA methyltransferase 1 in the transcriptional repression of long-terminal repeats. | 13 |
| 24075901 | 2013 | Three promoters regulate the transcriptional activity of the human holocarboxylase synthetase gene. | 3 |
| 24133061 | 2013 | Holocarboxylase synthetase catalyzes biotinylation of heat shock protein 72, thereby inducing RANTES expression in HEK-293 cells. | 4 |
Citation
Dessen P
HLCS (holocarboxylase synthetase)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/55984/hlcs-(holocarboxylase-synthetase)
