Identity
HGNC
LOCATION
Xp22.32
LOCUSID
ALIAS
ASPGX2,AUTSX2,HLNX,HNL4X,NLGN4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57502
MIM: 300427
HGNC: 14287
Ensembl: ENSG00000146938
Variants:
dbSNP: 57502
ClinVar: 57502
TCGA: ENSG00000146938
COSMIC: NLGN4X
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36747195 | 2023 | The distribution of neuroligin4, an autism-related postsynaptic molecule, in the human brain. | 2 |
| 36747195 | 2023 | The distribution of neuroligin4, an autism-related postsynaptic molecule, in the human brain. | 2 |
| 33268543 | 2021 | An Autism-Associated Mutation Impairs Neuroligin-4 Glycosylation and Enhances Excitatory Synaptic Transmission in Human Neurons. | 17 |
| 33369065 | 2021 | Pathogenic paternally inherited NLGN4X deletion in a female with autism spectrum disorder: Clinical, cytogenetic, and molecular characterization. | 3 |
| 34403115 | 2021 | RNA sequencing and functional studies of patient-derived cells reveal that neurexin-1 and regulators of this pathway are associated with poor outcomes in Ewing sarcoma. | 7 |
| 33268543 | 2021 | An Autism-Associated Mutation Impairs Neuroligin-4 Glycosylation and Enhances Excitatory Synaptic Transmission in Human Neurons. | 17 |
| 33369065 | 2021 | Pathogenic paternally inherited NLGN4X deletion in a female with autism spectrum disorder: Clinical, cytogenetic, and molecular characterization. | 3 |
| 34403115 | 2021 | RNA sequencing and functional studies of patient-derived cells reveal that neurexin-1 and regulators of this pathway are associated with poor outcomes in Ewing sarcoma. | 7 |
| 32243781 | 2020 | A Cluster of Autism-Associated Variants on X-Linked NLGN4X Functionally Resemble NLGN4Y. | 29 |
| 32873342 | 2020 | Autism-associated variants of neuroligin 4X impair synaptogenic activity by various molecular mechanisms. | 1 |
| 32243781 | 2020 | A Cluster of Autism-Associated Variants on X-Linked NLGN4X Functionally Resemble NLGN4Y. | 29 |
| 32873342 | 2020 | Autism-associated variants of neuroligin 4X impair synaptogenic activity by various molecular mechanisms. | 1 |
| 31257103 | 2019 | Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons. | 42 |
| 31257103 | 2019 | Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons. | 42 |
| 29622757 | 2018 | Significance of neurexin and neuroligin polymorphisms in regulating risk of Hirschsprung's disease. | 5 |
Citation
Dessen P
NLGN4X (neuroligin 4 X-linked)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/55987/nlgn4x-(neuroligin-4-x-linked)
