IFNE (interferon epsilon)

2016-10-01  

Identity

HGNC
LOCATION
9p21.3
LOCUSID
ALIAS
IFN-E,IFNE1,IFNT1,INFE1,PRO655

Other Information

Locus ID:

NCBI: 338376
MIM: 615223
HGNC: 18163
Ensembl: ENSG00000184995

Variants:

dbSNP: 338376
ClinVar: 338376
TCGA: ENSG00000184995
COSMIC: IFNE

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000184995ENST00000448696Q86WN2

Expression (GTEx)

0
1
2
3
4

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Jak-STAT signaling pathwayKEGGko04630
Cytokine-cytokine receptor interactionKEGGhsa04060
Jak-STAT signaling pathwayKEGGhsa04630
RIG-I-like receptor signaling pathwayKEGGko04622
RIG-I-like receptor signaling pathwayKEGGhsa04622

References

Pubmed IDYearTitleCitations
368979272023Constitutive expression and distinct properties of IFN-epsilon protect the female reproductive tract from Zika virus infection.6
375873352023Interferon-ε is a tumour suppressor and restricts ovarian cancer.6
381563992023Upregulation of IFNE in cervical biopsies of patients with high-risk human papillomavirus infections.0
368979272023Constitutive expression and distinct properties of IFN-epsilon protect the female reproductive tract from Zika virus infection.6
375873352023Interferon-ε is a tumour suppressor and restricts ovarian cancer.6
381563992023Upregulation of IFNE in cervical biopsies of patients with high-risk human papillomavirus infections.0
358622222022Spatiotemporal regulation of human IFN-ε and innate immunity in the female reproductive tract.8
358622222022Spatiotemporal regulation of human IFN-ε and innate immunity in the female reproductive tract.8
299050342018Interferon epsilon in the reproductive tract of healthy and genital herpes simplex virus-infected pregnant women: Results of a pilot study.8
299050342018Interferon epsilon in the reproductive tract of healthy and genital herpes simplex virus-infected pregnant women: Results of a pilot study.8
280450252017Interferon epsilon promotes HIV restriction at multiple steps of viral replication.18
280450252017Interferon epsilon promotes HIV restriction at multiple steps of viral replication.18
265557082016HIV-1-negative female sex workers sustain high cervical IFNɛ, low immune activation, and low expression of HIV-1-required host genes.17
279425842016IFN-ε protects primary macrophages against HIV infection.20
265557082016HIV-1-negative female sex workers sustain high cervical IFNɛ, low immune activation, and low expression of HIV-1-required host genes.17

Citation

Dessen P

IFNE (interferon epsilon)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/55988/teaching-explorer/meetings/