Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84286
MIM: 616660
HGNC: 28709
Ensembl: ENSG00000127419
Variants:
dbSNP: 84286
ClinVar: 84286
TCGA: ENSG00000127419
COSMIC: TMEM175
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37390818 | 2023 | Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel. | 13 |
| 37390818 | 2023 | Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel. | 13 |
| 33505021 | 2021 | A growth-factor-activated lysosomal K(+) channel regulates Parkinson's pathology. | 38 |
| 33505021 | 2021 | A growth-factor-activated lysosomal K(+) channel regulates Parkinson's pathology. | 38 |
| 31658403 | 2020 | Genetic, Structural, and Functional Evidence Link TMEM175 to Synucleinopathies. | 36 |
| 32228865 | 2020 | Gating and selectivity mechanisms for the lysosomal K(+) channel TMEM175. | 17 |
| 31658403 | 2020 | Genetic, Structural, and Functional Evidence Link TMEM175 to Synucleinopathies. | 36 |
| 32228865 | 2020 | Gating and selectivity mechanisms for the lysosomal K(+) channel TMEM175. | 17 |
| 31261387 | 2019 | Functionalization of the TMEM175 p.M393T variant as a risk factor for Parkinson disease. | 36 |
| 31261387 | 2019 | Functionalization of the TMEM175 p.M393T variant as a risk factor for Parkinson disease. | 36 |
| 28193887 | 2017 | TMEM175 deficiency impairs lysosomal and mitochondrial function and increases α-synuclein aggregation. | 108 |
| 28723891 | 2017 | The lysosomal potassium channel TMEM175 adopts a novel tetrameric architecture. | 35 |
| 28193887 | 2017 | TMEM175 deficiency impairs lysosomal and mitochondrial function and increases α-synuclein aggregation. | 108 |
| 28723891 | 2017 | The lysosomal potassium channel TMEM175 adopts a novel tetrameric architecture. | 35 |
| 25914293 | 2015 | Impact of Parkinson's disease risk loci on age at onset. | 20 |
Citation
Dessen P
TMEM175 (transmembrane protein 175)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56000/tmem175-(transmembrane-protein-175)
