Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55283
MIM: 607400
HGNC: 13358
Ensembl: ENSG00000055732
Variants:
dbSNP: 55283
ClinVar: 55283
TCGA: ENSG00000055732
COSMIC: MCOLN3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000055732 | ENST00000341115 | Q8TDD5 |
| ENSG00000055732 | ENST00000370587 | B1ANB7 |
| ENSG00000055732 | ENST00000370589 | Q8TDD5 |
| ENSG00000055732 | ENST00000490600 | S4R386 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30215288 | 2019 | Palmitoylation controls trafficking of the intracellular Ca(2+) channel MCOLN3/TRPML3 to regulate autophagy. | 24 |
| 30215288 | 2019 | Palmitoylation controls trafficking of the intracellular Ca(2+) channel MCOLN3/TRPML3 to regulate autophagy. | 24 |
| 29577631 | 2018 | The regulatory mechanism of mammalian TRPMLs revealed by cryo-EM. | 5 |
| 29577631 | 2018 | The regulatory mechanism of mammalian TRPMLs revealed by cryo-EM. | 5 |
| 24269818 | 2014 | The Ca2+ channel TRPML3 specifically interacts with the mammalian ATG8 homologue GATE16 to regulate autophagy. | 18 |
| 24269818 | 2014 | The Ca2+ channel TRPML3 specifically interacts with the mammalian ATG8 homologue GATE16 to regulate autophagy. | 18 |
| 23469151 | 2013 | A novel ion channel formed by interaction of TRPML3 with TRPV5. | 9 |
| 23469151 | 2013 | A novel ion channel formed by interaction of TRPML3 with TRPV5. | 9 |
| 22753890 | 2012 | Constitutive activity of TRPML2 and TRPML3 channels versus activation by low extracellular sodium and small molecules. | 17 |
| 22753890 | 2012 | Constitutive activity of TRPML2 and TRPML3 channels versus activation by low extracellular sodium and small molecules. | 17 |
| 19885840 | 2010 | Functional multimerization of mucolipin channel proteins. | 28 |
| 20378547 | 2010 | Properties of the TRPML3 channel pore and its stable expansion by the Varitint-Waddler-causing mutation. | 13 |
| 20736310 | 2010 | Heteromultimeric TRPML channel assemblies play a crucial role in the regulation of cell viability models and starvation-induced autophagy. | 32 |
| 19885840 | 2010 | Functional multimerization of mucolipin channel proteins. | 28 |
| 20378547 | 2010 | Properties of the TRPML3 channel pore and its stable expansion by the Varitint-Waddler-causing mutation. | 13 |
Citation
Dessen P
MCOLN3 (mucolipin TRP cation channel 3)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56004/mcoln3-(mucolipin-trp-cation-channel-3)
