Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 387715
MIM: 611313
HGNC: 32685
Ensembl: ENSG00000254636
Variants:
dbSNP: 387715
ClinVar: 387715
TCGA: ENSG00000254636
COSMIC: ARMS2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000254636 | ENST00000528446 | P0C7Q2 |
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA130232992 | bevacizumab | Chemical | ClinicalAnnotation | associated | PD | 22594510 | |
| PA134850558 | Macular Degeneration | Disease | ClinicalAnnotation | associated | PD | 22594510 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37717737 | 2024 | Critical Dependence on Area in Relationship between ARMS2/HTRA1 Genotype and Faster Geographic Atrophy Enlargement: Age-Related Eye Disease Study 2 Report Number 33. | 0 |
| 37717737 | 2024 | Critical Dependence on Area in Relationship between ARMS2/HTRA1 Genotype and Faster Geographic Atrophy Enlargement: Age-Related Eye Disease Study 2 Report Number 33. | 0 |
| 36481221 | 2023 | Reticular Pseudodrusen Status, ARMS2/HTRA1 Genotype, and Geographic Atrophy Enlargement: Age-Related Eye Disease Study 2 Report 32. | 8 |
| 36581531 | 2023 | Exploring the contribution of ARMS2 and HTRA1 genetic risk factors in age-related macular degeneration. | 7 |
| 36734065 | 2023 | Associations of ARMS2 and NR3C2 genes polymorphisms with central serous chorioretinopathy in a Greek population. | 0 |
| 37085233 | 2023 | Disentangling the Impact of Reticular Pseudodrusen Phenotype and the ARMS2/HTRA1 Risk Allele in Geographic Atrophy: The AREDS 2 Study Report 32. | 0 |
| 36481221 | 2023 | Reticular Pseudodrusen Status, ARMS2/HTRA1 Genotype, and Geographic Atrophy Enlargement: Age-Related Eye Disease Study 2 Report 32. | 8 |
| 36581531 | 2023 | Exploring the contribution of ARMS2 and HTRA1 genetic risk factors in age-related macular degeneration. | 7 |
| 36734065 | 2023 | Associations of ARMS2 and NR3C2 genes polymorphisms with central serous chorioretinopathy in a Greek population. | 0 |
| 37085233 | 2023 | Disentangling the Impact of Reticular Pseudodrusen Phenotype and the ARMS2/HTRA1 Risk Allele in Geographic Atrophy: The AREDS 2 Study Report 32. | 0 |
| 35236246 | 2022 | Role of CFH Y402H and ARMS2 A69S polymorphisms in susceptibility to post rhegmatogenous retinal detachment macular complications. | 0 |
| 35240203 | 2022 | The Phenotypic Course of Age-Related Macular Degeneration for ARMS2/HTRA1: The EYE-RISK Consortium. | 9 |
| 35236246 | 2022 | Role of CFH Y402H and ARMS2 A69S polymorphisms in susceptibility to post rhegmatogenous retinal detachment macular complications. | 0 |
| 35240203 | 2022 | The Phenotypic Course of Age-Related Macular Degeneration for ARMS2/HTRA1: The EYE-RISK Consortium. | 9 |
| 32428913 | 2021 | Meta-Analysis of the Pharmacogenetics of ARMS2 A69S Polymorphism and the Response to Advanced Age-Related Macular Degeneration. | 7 |
Citation
Dessen P
ARMS2 (age-related maculopathy susceptibility 2)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56007/arms2-(age-related-maculopathy-susceptibility-2)
