Identity
HGNC
LOCATION
20p13
LOCUSID
ALIAS
P47,UBX1,UBXD10,UBXN2C,dJ776F14.1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55968
MIM: 606610
HGNC: 15912
Ensembl: ENSG00000088833
Variants:
dbSNP: 55968
ClinVar: 55968
TCGA: ENSG00000088833
COSMIC: NSFL1C
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Protein processing in endoplasmic reticulum | KEGG | ko04141 |
| Protein processing in endoplasmic reticulum | KEGG | hsa04141 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35475466 | 2022 | Translocator protein (18 kDa) regulates the microglial phenotype in Parkinson's disease through P47. | 2 |
| 35475466 | 2022 | Translocator protein (18 kDa) regulates the microglial phenotype in Parkinson's disease through P47. | 2 |
| 33555040 | 2021 | p97 and p47 function in membrane tethering in cooperation with FTCD during mitotic Golgi reassembly. | 10 |
| 33555040 | 2021 | p97 and p47 function in membrane tethering in cooperation with FTCD during mitotic Golgi reassembly. | 10 |
| 30837480 | 2019 | Degradation of p47 by autophagy contributes to CADM1 overexpression in ATLL cells through the activation of NF-κB. | 10 |
| 30837480 | 2019 | Degradation of p47 by autophagy contributes to CADM1 overexpression in ATLL cells through the activation of NF-κB. | 10 |
| 27785701 | 2017 | The opposite role of two UBA-UBX containing proteins, p47 and SAKS1 in the degradation of a single ERAD substrate, α-TCR. | 7 |
| 27785701 | 2017 | The opposite role of two UBA-UBX containing proteins, p47 and SAKS1 in the degradation of a single ERAD substrate, α-TCR. | 7 |
| 24612679 | 2014 | Brain-derived neurotrophic factor promotes angiogenic tube formation through generation of oxidative stress in human vascular endothelial cells. | 26 |
| 24612679 | 2014 | Brain-derived neurotrophic factor promotes angiogenic tube formation through generation of oxidative stress in human vascular endothelial cells. | 26 |
| 23649807 | 2013 | The UBXN-2/p37/p47 adaptors of CDC-48/p97 regulate mitosis by limiting the centrosomal recruitment of Aurora A. | 14 |
| 23649807 | 2013 | The UBXN-2/p37/p47 adaptors of CDC-48/p97 regulate mitosis by limiting the centrosomal recruitment of Aurora A. | 14 |
| 22990857 | 2012 | p47 negatively regulates IKK activation by inducing the lysosomal degradation of polyubiquitinated NEMO. | 32 |
| 22990857 | 2012 | p47 negatively regulates IKK activation by inducing the lysosomal degradation of polyubiquitinated NEMO. | 32 |
| 19165527 | 2009 | Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia. | 69 |
Citation
Dessen P
NSFL1C (NSFL1 cofactor)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56008/nsfl1c-(nsfl1-cofactor)
