Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8778
MIM: 604200
HGNC: 10874
Ensembl: ENSG00000105501
Variants:
dbSNP: 8778
ClinVar: 8778
TCGA: ENSG00000105501
COSMIC: SIGLEC5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000105501 | ENST00000534261 | O15389 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36129033 | 2023 | Case-only design identifies interactions of genetic risk variants at SIGLEC5 and PLG with the lncRNA CTD-2353F22.1 implying the importance of periodontal wound healing for disease aetiology. | 3 |
| 37854605 | 2023 | PSGL-1: a novel immune checkpoint driving T-cell dysfunction in obstructive sleep apnea. | 0 |
| 37890368 | 2023 | The prognostic impact of SIGLEC5-induced impairment of CD8(+) T cell activation in sepsis. | 3 |
| 36129033 | 2023 | Case-only design identifies interactions of genetic risk variants at SIGLEC5 and PLG with the lncRNA CTD-2353F22.1 implying the importance of periodontal wound healing for disease aetiology. | 3 |
| 37854605 | 2023 | PSGL-1: a novel immune checkpoint driving T-cell dysfunction in obstructive sleep apnea. | 0 |
| 37890368 | 2023 | The prognostic impact of SIGLEC5-induced impairment of CD8(+) T cell activation in sepsis. | 3 |
| 34852650 | 2022 | Periodontitis Risk Variants at SIGLEC5 Impair ERG and MAFB Binding. | 4 |
| 35290663 | 2022 | Siglec-5 is an inhibitory immune checkpoint molecule for human T cells. | 12 |
| 36116391 | 2022 | Siglec-5 and Siglec-14 mediate the endocytosis of ADAMTS13. | 0 |
| 34852650 | 2022 | Periodontitis Risk Variants at SIGLEC5 Impair ERG and MAFB Binding. | 4 |
| 35290663 | 2022 | Siglec-5 is an inhibitory immune checkpoint molecule for human T cells. | 12 |
| 36116391 | 2022 | Siglec-5 and Siglec-14 mediate the endocytosis of ADAMTS13. | 0 |
| 30765789 | 2019 | Genetic susceptibility of common polymorphisms in NIN and SIGLEC5 to chronic periodontitis. | 8 |
| 30922727 | 2019 | Soluble siglec-5 is a novel salivary biomarker for primary Sjogren's syndrome. | 10 |
| 30765789 | 2019 | Genetic susceptibility of common polymorphisms in NIN and SIGLEC5 to chronic periodontitis. | 8 |
Citation
Dessen P
SIGLEC5 (sialic acid binding Ig like lectin 5)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56013/siglec5-(sialic-acid-binding-ig-like-lectin-5)
