Identity
HGNC
LOCATION
11q12.2
LOCUSID
ALIAS
C11orf11,DAGL(ALPHA),DAGLALPHA,NSDDR
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 747
MIM: 614015
HGNC: 1165
Ensembl: ENSG00000134780
Variants:
dbSNP: 747
ClinVar: 747
TCGA: ENSG00000134780
COSMIC: DAGLA
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000134780 | ENST00000257215 | Q9Y4D2 |
| ENSG00000134780 | ENST00000257215 | A0A024R517 |
| ENSG00000134780 | ENST00000540717 | F5GY58 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37414748 | 2023 | Diacylglycerol lipase alpha promotes hepatocellular carcinoma progression and induces lenvatinib resistance by enhancing YAP activity. | 2 |
| 37414748 | 2023 | Diacylglycerol lipase alpha promotes hepatocellular carcinoma progression and induces lenvatinib resistance by enhancing YAP activity. | 2 |
| 29477030 | 2018 | Association between alcoholism and the gene encoding the endocannabinoid synthesizing enzyme diacylglycerol lipase alpha in the Japanese population. | 3 |
| 29614312 | 2018 | Diacylglycerol lipase alpha promotes tumorigenesis in oral cancer by cell-cycle progression. | 5 |
| 29477030 | 2018 | Association between alcoholism and the gene encoding the endocannabinoid synthesizing enzyme diacylglycerol lipase alpha in the Japanese population. | 3 |
| 29614312 | 2018 | Diacylglycerol lipase alpha promotes tumorigenesis in oral cancer by cell-cycle progression. | 5 |
| 29145497 | 2017 | Rare genetic variants in the endocannabinoid system genes CNR1 and DAGLA are associated with neurological phenotypes in humans. | 25 |
| 29145497 | 2017 | Rare genetic variants in the endocannabinoid system genes CNR1 and DAGLA are associated with neurological phenotypes in humans. | 25 |
| 24076015 | 2014 | Nuclear phospholipase C-β1 and diacylglycerol LIPASE-α in brain cortical neurons. | 16 |
| 24616451 | 2014 | Influence of dietary fat intake on the endocannabinoid system in lean and obese subjects. | 22 |
| 24076015 | 2014 | Nuclear phospholipase C-β1 and diacylglycerol LIPASE-α in brain cortical neurons. | 16 |
| 24616451 | 2014 | Influence of dietary fat intake on the endocannabinoid system in lean and obese subjects. | 22 |
| 22827915 | 2012 | Developmental trajectory of the endocannabinoid system in human dorsolateral prefrontal cortex. | 40 |
| 22827915 | 2012 | Developmental trajectory of the endocannabinoid system in human dorsolateral prefrontal cortex. | 40 |
| 14610053 | 2003 | Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. | 403 |
Citation
Dessen P
DAGLA (diacylglycerol lipase alpha)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56014/dagla-(diacylglycerol-lipase-alpha)
