Identity
HGNC
LOCATION
15q24.2
LOCUSID
ALIAS
FBX22,FISTC1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26263
MIM: 609096
HGNC: 13593
Ensembl: ENSG00000167196
Variants:
dbSNP: 26263
ClinVar: 26263
TCGA: ENSG00000167196
COSMIC: FBXO22
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38673728 | 2024 | TANK Binding Kinase 1 Promotes BACH1 Degradation through Both Phosphorylation-Dependent and -Independent Mechanisms without Relying on Heme and FBXO22. | 0 |
| 38673728 | 2024 | TANK Binding Kinase 1 Promotes BACH1 Degradation through Both Phosphorylation-Dependent and -Independent Mechanisms without Relying on Heme and FBXO22. | 0 |
| 36112263 | 2023 | Fbxo22 inhibits metastasis in triple-negative breast cancer through ubiquitin modification of KDM5A and regulation of H3K4me3 demethylation. | 5 |
| 36515852 | 2023 | FBXO22 Accelerates Pancreatic Cancer Growth by Deactivation of the Hippo Pathway via Destabilizing LATS2. | 1 |
| 36774506 | 2023 | FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia. | 4 |
| 37442264 | 2023 | FBXO22 inhibits proliferation and metastasis of cervical cancer cells by mediating ubiquitination-dependent degradation of GAK. | 2 |
| 37519006 | 2023 | ELK4 Promotes Cell Cycle Progression and Stem Cell-like Characteristics in HPV-associated Cervical Cancer by Regulating the FBXO22/PTEN Axis. | 0 |
| 36112263 | 2023 | Fbxo22 inhibits metastasis in triple-negative breast cancer through ubiquitin modification of KDM5A and regulation of H3K4me3 demethylation. | 5 |
| 36515852 | 2023 | FBXO22 Accelerates Pancreatic Cancer Growth by Deactivation of the Hippo Pathway via Destabilizing LATS2. | 1 |
| 36774506 | 2023 | FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia. | 4 |
| 37442264 | 2023 | FBXO22 inhibits proliferation and metastasis of cervical cancer cells by mediating ubiquitination-dependent degradation of GAK. | 2 |
| 37519006 | 2023 | ELK4 Promotes Cell Cycle Progression and Stem Cell-like Characteristics in HPV-associated Cervical Cancer by Regulating the FBXO22/PTEN Axis. | 0 |
| 34215846 | 2022 | Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an ERK-FBXO22-BAG3 axis in tumorigenesis. | 12 |
| 36127346 | 2022 | Fbxo22 promotes cervical cancer progression via targeting p57(Kip2) for ubiquitination and degradation. | 10 |
| 34215846 | 2022 | Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an ERK-FBXO22-BAG3 axis in tumorigenesis. | 12 |
Citation
Dessen P
FBXO22 (F-box protein 22)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56035/fbxo22-(f-box-protein-22)
