Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 53918
MIM: 605757
HGNC: 8829
Ensembl: ENSG00000152684
Variants:
dbSNP: 53918
ClinVar: 53918
TCGA: ENSG00000152684
COSMIC: PELO
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000152684 | ENST00000274311 | Q9BRX2 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| mRNA surveillance pathway | KEGG | ko03015 |
| mRNA surveillance pathway | KEGG | hsa03015 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36948192 | 2023 | Ribosome-rescuer PELO catalyzes the oligomeric assembly of NOD-like receptor family proteins via activating their ATPase enzymatic activity. | 6 |
| 36948192 | 2023 | Ribosome-rescuer PELO catalyzes the oligomeric assembly of NOD-like receptor family proteins via activating their ATPase enzymatic activity. | 6 |
| 28213379 | 2017 | Slowed decay of mRNAs enhances platelet specific translation. | 36 |
| 28213379 | 2017 | Slowed decay of mRNAs enhances platelet specific translation. | 36 |
| 27543824 | 2016 | Conserved functions of human Pelota in mRNA quality control of nonstop mRNA. | 10 |
| 27681415 | 2016 | Dynamic Regulation of a Ribosome Rescue Pathway in Erythroid Cells and Platelets. | 75 |
| 27543824 | 2016 | Conserved functions of human Pelota in mRNA quality control of nonstop mRNA. | 10 |
| 27681415 | 2016 | Dynamic Regulation of a Ribosome Rescue Pathway in Erythroid Cells and Platelets. | 75 |
| 23435426 | 2014 | PELO negatively regulates HER receptor signalling and metastasis. | 8 |
| 23435426 | 2014 | PELO negatively regulates HER receptor signalling and metastasis. | 8 |
| 23667253 | 2013 | The Hbs1-Dom34 protein complex functions in non-stop mRNA decay in mammalian cells. | 43 |
| 23667253 | 2013 | The Hbs1-Dom34 protein complex functions in non-stop mRNA decay in mammalian cells. | 43 |
| 21448132 | 2011 | Dissociation by Pelota, Hbs1 and ABCE1 of mammalian vacant 80S ribosomes and stalled elongation complexes. | 172 |
| 21448132 | 2011 | Dissociation by Pelota, Hbs1 and ABCE1 of mammalian vacant 80S ribosomes and stalled elongation complexes. | 172 |
| 20306291 | 2010 | A three-stage genome-wide association study of general cognitive ability: hunting the small effects. | 40 |
Citation
Dessen P
PELO (pelota mRNA surveillance and ribosome rescue factor)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56038/pelo-(pelota-mrna-surveillance-and-ribosome-rescue-factor)
