GPR12 (G protein-coupled receptor 12)

2016-10-01  

Identity

HGNC
LOCATION
13q12.13
LOCUSID
ALIAS
GPCR12,GPCR21,PPP1R84

Other Information

Locus ID:

NCBI: 2835
MIM: 600752
HGNC: 4466
Ensembl: ENSG00000132975

Variants:

dbSNP: 2835
ClinVar: 2835
TCGA: ENSG00000132975
COSMIC: GPR12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132975ENST00000381436P47775
ENSG00000132975ENST00000381436A8K2F5
ENSG00000132975ENST00000405846P47775
ENSG00000132975ENST00000405846A8K2F5

Expression (GTEx)

0
5
10
15
20
25

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
365931622023Structural insight into the constitutive activity of human orphan receptor GPR12.5
377893532023Exosomal miR-105-5p derived from bladder cancer stem cells targets for GPR12 to promote the malignancy of bladder cancer.1
365931622023Structural insight into the constitutive activity of human orphan receptor GPR12.5
377893532023Exosomal miR-105-5p derived from bladder cancer stem cells targets for GPR12 to promote the malignancy of bladder cancer.1
337427712021GPR12 inhibits migration and promotes apoptosis in esophageal cancer and hypopharyngeal cancer cells.8
337427712021GPR12 inhibits migration and promotes apoptosis in esophageal cancer and hypopharyngeal cancer cells.8
288889842017Cannabidiol, a novel inverse agonist for GPR12.22
288889842017Cannabidiol, a novel inverse agonist for GPR12.22
224309502012Involvement of GPR12 in the regulation of cell proliferation and survival.10
224309502012Involvement of GPR12 in the regulation of cell proliferation and survival.10
126495922003Fluid shear stress differentially regulates gpr3, gpr6, and gpr12 expression in human umbilical vein endothelial cells.9
126495922003Fluid shear stress differentially regulates gpr3, gpr6, and gpr12 expression in human umbilical vein endothelial cells.9

Citation

Dessen P

GPR12 (G protein-coupled receptor 12)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56043/gpr12-(g-protein-coupled-receptor-12)