TMED5 (transmembrane p24 trafficking protein 5)

2016-10-01  

Identity

HGNC
TMED5
LOCATION
1p22.1
LOCUSID
50999
ALIAS
CGI-100,p24g2,p28
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 50999
MIM: 616876
HGNC: 24251
Ensembl: ENSG00000117500

Variants:

dbSNP: 50999
ClinVar: 50999
TCGA: ENSG00000117500
COSMIC: TMED5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000117500ENST00000370280B1AKT3
ENSG00000117500ENST00000370282Q9Y3A6
ENSG00000117500ENST00000370290M0R072
ENSG00000117500ENST00000479918Q9Y3A6

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by WntREACTOMER-HSA-195721
WNT ligand biogenesis and traffickingREACTOMER-HSA-3238698

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
365300302023Silencing of TMED5 inhibits proliferation, migration and invasion, and enhances apoptosis of hepatocellular carcinoma cells.3
365300302023Silencing of TMED5 inhibits proliferation, migration and invasion, and enhances apoptosis of hepatocellular carcinoma cells.3
344043912021Identification of a novel circ_0018289/miR-183-5p/TMED5 regulatory network in cervical cancer development.6
344043912021Identification of a novel circ_0018289/miR-183-5p/TMED5 regulatory network in cervical cancer development.6
247781902014The α-helical region in p24γ2 subunit of p24 protein cargo receptor is pivotal for the recognition and transport of glycosylphosphatidylinositol-anchored proteins.11
247781902014The α-helical region in p24γ2 subunit of p24 protein cargo receptor is pivotal for the recognition and transport of glycosylphosphatidylinositol-anchored proteins.11
185496222008[Effects of matrine on cgi-100 gene expression and proliferation in K562 cells].0
185496222008[Effects of matrine on cgi-100 gene expression and proliferation in K562 cells].0

Citation

Dessen P

TMED5 (transmembrane p24 trafficking protein 5)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56056/tmed5-(transmembrane-p24-trafficking-protein-5)