Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2555
MIM: 137140
HGNC: 4076
Ensembl: ENSG00000151834
Variants:
dbSNP: 2555
ClinVar: 2555
TCGA: ENSG00000151834
COSMIC: GABRA2
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA446878 | Cocaine-Related Disorders | Disease | ClinicalAnnotation | associated | PD | ||
| PA449072 | cocaine | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36469977 | 2023 | Novel variants in GABA(A) receptor subunits: A possible association with benzodiazepine resistance in patients with drug-resistant epilepsy. | 2 |
| 36469977 | 2023 | Novel variants in GABA(A) receptor subunits: A possible association with benzodiazepine resistance in patients with drug-resistant epilepsy. | 2 |
| 36422192 | 2022 | Prospective DNA Methylation Analysis of the CpG GABRA2 Receptor Subunit in Alcohol Dependence during Detoxification. | 0 |
| 36422192 | 2022 | Prospective DNA Methylation Analysis of the CpG GABRA2 Receptor Subunit in Alcohol Dependence during Detoxification. | 0 |
| 33128845 | 2021 | Longitudinal Links between Adolescent and Peer Conduct Problems and Moderation by a Sensitivity Genetic Index. | 1 |
| 34086081 | 2021 | Gabra2 is a genetic modifier of Dravet syndrome in mice. | 12 |
| 33128845 | 2021 | Longitudinal Links between Adolescent and Peer Conduct Problems and Moderation by a Sensitivity Genetic Index. | 1 |
| 34086081 | 2021 | Gabra2 is a genetic modifier of Dravet syndrome in mice. | 12 |
| 32376074 | 2020 | Gene expression meta-analysis reveals the down-regulation of three GABA receptor subunits in the superior temporal gyrus of patients with schizophrenia. | 5 |
| 32446246 | 2020 | FRMD7 Mutations Disrupt the Interaction with GABRA2 and May Result in Infantile Nystagmus Syndrome. | 6 |
| 33140451 | 2020 | Gabra2 is a genetic modifier of Scn8a encephalopathy in the mouse. | 14 |
| 32376074 | 2020 | Gene expression meta-analysis reveals the down-regulation of three GABA receptor subunits in the superior temporal gyrus of patients with schizophrenia. | 5 |
| 32446246 | 2020 | FRMD7 Mutations Disrupt the Interaction with GABRA2 and May Result in Infantile Nystagmus Syndrome. | 6 |
| 33140451 | 2020 | Gabra2 is a genetic modifier of Scn8a encephalopathy in the mouse. | 14 |
| 31790348 | 2019 | Effects of Common and Rare Chromosome 4 GABAergic Gene Variation on Alcohol Use and Antisocial Behavior. | 0 |
Citation
Dessen P
GABRA2 (gamma-aminobutyric acid type A receptor subunit alpha2)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56060/gabra2-(gamma-aminobutyric-acid-type-a-receptor-subunit-alpha2)
