DIMT1 (DIM1 rRNA methyltransferase and ribosome maturation factor)

2016-10-01  

Identity

HGNC
LOCATION
5q12.1
LOCUSID
ALIAS
DIM1,DIMT1L,HSA9761,HUSSY5
FUSION GENES

Other Information

Locus ID:

NCBI: 27292
MIM: 612499
HGNC: 30217
Ensembl: ENSG00000086189

Variants:

dbSNP: 27292
ClinVar: 27292
TCGA: ENSG00000086189
COSMIC: DIMT1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000086189ENST00000199320Q9UNQ2
ENSG00000086189ENST00000506390A0A0C4DGB1
ENSG00000086189ENST00000514911D6RCL3
ENSG00000086189ENST00000651114A0A494C0G7

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
rRNA processingREACTOMER-HSA-72312
rRNA modification in the nucleus and cytosolREACTOMER-HSA-6790901
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
251871772014Epigenetic silencing of miR-210 increases the proliferation of gastric epithelium during chronic Helicobacter pylori infection.34
258516042015The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis.26
281644102017Hypoxia-inducible microRNA-210 regulates the DIMT1-IRF4 oncogenic axis in multiple myeloma.8
286016612017DIMT1 overexpression correlates with progression and prognosis in gastric carcinoma.0

Citation

Dessen P

DIMT1 (DIM1 rRNA methyltransferase and ribosome maturation factor)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56066/dimt1-(dim1-rrna-methyltransferase-and-ribosome-maturation-factor)