MIEF1 (mitochondrial elongation factor 1)

2016-10-01  

Identity

HGNC
LOCATION
22q13.1
LOCUSID
ALIAS
AltMIEF1,HSU79252,MID51,MIEF1-MP,SMCR7L,dJ1104E15.3
FUSION GENES

Other Information

Locus ID:

NCBI: 54471
MIM: 615497
HGNC: 25979
Ensembl: ENSG00000100335

Variants:

dbSNP: 54471
ClinVar: 54471
TCGA: ENSG00000100335
COSMIC: MIEF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100335ENST00000325301Q9NQG6
ENSG00000100335ENST00000325301A0A024R1L3
ENSG00000100335ENST00000402881B0QY95
ENSG00000100335ENST00000404569Q9NQG6
ENSG00000100335ENST00000404569A0A024R1L3
ENSG00000100335ENST00000428069Q9NQG6
ENSG00000100335ENST00000433117Q9NQG6
ENSG00000100335ENST00000434364B0QY94

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

References

Pubmed IDYearTitleCitations
371499862023Ischemia/reperfusion-induced MiD51 upregulation recruits Drp1 to mitochondria and contributes to myocardial injury.1
371499862023Ischemia/reperfusion-induced MiD51 upregulation recruits Drp1 to mitochondria and contributes to myocardial injury.1
360440222022Mid51/Fis1 mitochondrial oligomerization complex drives lysosomal untethering and network dynamics.10
360440222022Mid51/Fis1 mitochondrial oligomerization complex drives lysosomal untethering and network dynamics.10
336322692021Dominant mutations in MIEF1 affect mitochondrial dynamics and cause a singular late onset optic neuropathy.11
336322692021Dominant mutations in MIEF1 affect mitochondrial dynamics and cause a singular late onset optic neuropathy.11
320683122020An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications.9
320683122020An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications.9
308940732019Loss of MIEF1/MiD51 confers susceptibility to BAX-mediated cell death and PINK1-PRKN-dependent mitophagy.25
315339862019The phosphorylation status of Ser-637 in dynamin-related protein 1 (Drp1) does not determine Drp1 recruitment to mitochondria.45
308940732019Loss of MIEF1/MiD51 confers susceptibility to BAX-mediated cell death and PINK1-PRKN-dependent mitophagy.25
315339862019The phosphorylation status of Ser-637 in dynamin-related protein 1 (Drp1) does not determine Drp1 recruitment to mitochondria.45
294316432018Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications.82
302155122018MIEF1 Microprotein Regulates Mitochondrial Translation.48
294316432018Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications.82

Citation

Dessen P

MIEF1 (mitochondrial elongation factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56068/mief1-(mitochondrial-elongation-factor-1)