CKLF (chemokine like factor)

2016-10-01  

Identity

HGNC
CKLF
LOCATION
16q21
LOCUSID
51192
ALIAS
C32,CKLF1,CKLF2,CKLF3,CKLF4,HSPC224,UCK-1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51192
MIM: 616074
HGNC: 13253
Ensembl: ENSG00000217555

Variants:

dbSNP: 51192
ClinVar: 51192
TCGA: ENSG00000217555
COSMIC: CKLF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000217555ENST00000264001Q9UBR5
ENSG00000217555ENST00000351137Q5BJH6
ENSG00000217555ENST00000534692E9PLU7

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
180690422008Two C-terminal peptides of human CKLF1 interact with the chemokine receptor CCR4.8
203924392010Expressional and functional studies of CKLF1 during dendritic cell maturation.7
239836092013Chemokine-like factor 1 (CLFK1) is over-expressed in patients with atopic dermatitis.7
259157462015Chemokine-like factor 1-derived C-terminal peptides induce the proliferation of dermal microvascular endothelial cells in psoriasis.6
269861422016Chemokine-Like Factor 1 (CKLF-1) is Overexpressed in Keloid Patients: A Potential Indicating Factor for Keloid-Predisposed Individuals.6
124110602002Effects of novel human chemokine-like factor 1 (CKLF1) on bone marrow hematopoietic stem cell/progenitor cell in vitro.5
182943402008Chemokine-like factor expression in the idiopathic inflammatory myopathies.5
268387432016Distinct expression of chemokine-like factor 1 in synovium of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.3
271535592016Stratified analysis reveals chemokine-like factor (CKLF) as a potential prognostic marker in the MSI-immune consensus molecular subtype CMS1 of colorectal cancer.3

Citation

Dessen P

CKLF (chemokine like factor)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56077/cklf-(chemokine-like-factor)