Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3745
MIM: 600397
HGNC: 6231
Ensembl: ENSG00000158445
Variants:
dbSNP: 3745
ClinVar: 3745
TCGA: ENSG00000158445
COSMIC: KCNB1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000158445 | ENST00000371741 | Q14721 |
| ENSG00000158445 | ENST00000635465 | Q14721 |
| ENSG00000158445 | ENST00000635878 | A0A1B0GU02 |
| ENSG00000158445 | ENST00000637131 | A0A1B0GTM8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37758949 | 2023 | Inactivation of the Kv2.1 channel through electromechanical coupling. | 5 |
| 37758949 | 2023 | Inactivation of the Kv2.1 channel through electromechanical coupling. | 5 |
| 34915430 | 2022 | Adaptive behavior and psychiatric comorbidities in KCNB1 encephalopathy. | 1 |
| 35231557 | 2022 | Cleavage of Kv2.1 by BACE1 decreases potassium current and reduces neuronal apoptosis. | 2 |
| 34915430 | 2022 | Adaptive behavior and psychiatric comorbidities in KCNB1 encephalopathy. | 1 |
| 35231557 | 2022 | Cleavage of Kv2.1 by BACE1 decreases potassium current and reduces neuronal apoptosis. | 2 |
| 33407994 | 2021 | The role of the voltage-gated potassium channel, Kv2.1 in prostate cancer cell migration. | 6 |
| 33607466 | 2021 | Establishment of an induced pluripotent stem cell line (ZJSHi001-A) from a patient with epileptic encephalopathy carrying KCNB1 Glu330Asp mutation. | 1 |
| 34137443 | 2021 | Kv2 channel-AMIGO β-subunit assembly modulates both channel function and cell adhesion molecule surface trafficking. | 5 |
| 33407994 | 2021 | The role of the voltage-gated potassium channel, Kv2.1 in prostate cancer cell migration. | 6 |
| 33607466 | 2021 | Establishment of an induced pluripotent stem cell line (ZJSHi001-A) from a patient with epileptic encephalopathy carrying KCNB1 Glu330Asp mutation. | 1 |
| 34137443 | 2021 | Kv2 channel-AMIGO β-subunit assembly modulates both channel function and cell adhesion molecule surface trafficking. | 5 |
| 31513310 | 2020 | Expanding the genetic and phenotypic relevance of KCNB1 variants in developmental and epileptic encephalopathies: 27 new patients and overview of the literature. | 17 |
| 32484056 | 2020 | KCNB1 gene polymorphisms and related indel as predictor biomarkers of treatment response for colorectal cancer - toward a personalized medicine. | 4 |
| 32954514 | 2020 | Developmental and epilepsy spectrum of KCNB1 encephalopathy with long-term outcome. | 8 |
Citation
Dessen P
KCNB1 (potassium voltage-gated channel subfamily B member 1)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56087/kcnb1-(potassium-voltage-gated-channel-subfamily-b-member-1)
