Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84501
MIM: 609217
HGNC: 30623
Ensembl: ENSG00000204991
Variants:
dbSNP: 84501
ClinVar: 84501
TCGA: ENSG00000204991
COSMIC: SPIRE2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000204991 | ENST00000378247 | Q8WWL2 |
| ENSG00000204991 | ENST00000393062 | Q8WWL2 |
| ENSG00000204991 | ENST00000563972 | H3BV39 |
| ENSG00000204991 | ENST00000566337 | H3BV74 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Dorso-ventral axis formation | KEGG | ko04320 |
| Dorso-ventral axis formation | KEGG | hsa04320 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 27627128 | 2016 | A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion. | 10 |
| 27627128 | 2016 | A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion. | 10 |
| 25564607 | 2015 | Membrane targeting of the Spir·formin actin nucleator complex requires a sequential handshake of polar interactions. | 12 |
| 26287480 | 2015 | DNA damage induces nuclear actin filament assembly by Formin -2 and Spire-½ that promotes efficient DNA repair. [corrected]. | 109 |
| 25564607 | 2015 | Membrane targeting of the Spir·formin actin nucleator complex requires a sequential handshake of polar interactions. | 12 |
| 26287480 | 2015 | DNA damage induces nuclear actin filament assembly by Formin -2 and Spire-½ that promotes efficient DNA repair. [corrected]. | 109 |
| 19605360 | 2009 | Identification of a short Spir interaction sequence at the C-terminal end of formin subgroup proteins. | 34 |
| 19605360 | 2009 | Identification of a short Spir interaction sequence at the C-terminal end of formin subgroup proteins. | 34 |
Citation
Dessen P
SPIRE2 (spire type actin nucleation factor 2)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56103/spire2-(spire-type-actin-nucleation-factor-2)
