TMIGD2 (transmembrane and immunoglobulin domain containing 2)

2016-10-01  

Identity

HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
CD28H,IGPR-1,IGPR1

Other Information

Locus ID:

NCBI: 126259
MIM: 614715
HGNC: 28324
Ensembl: ENSG00000167664

Variants:

dbSNP: 126259
ClinVar: 126259
TCGA: ENSG00000167664
COSMIC: TMIGD2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167664ENST00000301272Q96BF3
ENSG00000167664ENST00000595645Q96BF3
ENSG00000167664ENST00000600114A0A0B4J2A9
ENSG00000167664ENST00000600349A0A0B4J2B0

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
359330912023KIR3DL3-HHLA2 and TMIGD2-HHLA2 pathways: The dual role of HHLA2 in immune responses and its potential therapeutic approach for cancer immunotherapy.14
372613622023TMIGD2 as a potential therapeutic target in glioma patients.2
359330912023KIR3DL3-HHLA2 and TMIGD2-HHLA2 pathways: The dual role of HHLA2 in immune responses and its potential therapeutic approach for cancer immunotherapy.14
372613622023TMIGD2 as a potential therapeutic target in glioma patients.2
351754962022HHLA2 Activates the JAK/STAT Signaling Pathway by Binding to TMIGD2 in Hepatocellular Carcinoma Cells.6
351754962022HHLA2 Activates the JAK/STAT Signaling Pathway by Binding to TMIGD2 in Hepatocellular Carcinoma Cells.6
339626302021NEDD4 regulates ubiquitination and stability of the cell adhesion molecule IGPR-1 via lysosomal pathway.12
339626302021NEDD4 regulates ubiquitination and stability of the cell adhesion molecule IGPR-1 via lysosomal pathway.12
318833032020Overexpression of B7H5/CD28H is associated with worse survival in human gastric cancer.9
319011782020Phenotypical and potential functional characteristics of different immune cells expressing CD28H/B7-H5 and their relationship with cancer prognosis.11
329782582020Cell adhesion molecule IGPR-1 activates AMPK connecting cell adhesion to autophagy.6
318833032020Overexpression of B7H5/CD28H is associated with worse survival in human gastric cancer.9
319011782020Phenotypical and potential functional characteristics of different immune cells expressing CD28H/B7-H5 and their relationship with cancer prognosis.11
329782582020Cell adhesion molecule IGPR-1 activates AMPK connecting cell adhesion to autophagy.6
305484412019B7-H5/CD28H is a co-stimulatory pathway and correlates with improved prognosis in pancreatic ductal adenocarcinoma.16

Citation

Dessen P

TMIGD2 (transmembrane and immunoglobulin domain containing 2)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56115/tmigd2-(transmembrane-and-immunoglobulin-domain-containing-2)