NKAP (NFKB activating protein)

2016-10-01  

Identity

HGNC
LOCATION
Xq24
LOCUSID
ALIAS
MRXSHD

Other Information

Locus ID:

NCBI: 79576
MIM: 300766
HGNC: 29873
Ensembl: ENSG00000101882

Variants:

dbSNP: 79576
ClinVar: 79576
TCGA: ENSG00000101882
COSMIC: NKAP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101882ENST00000371410Q8N5F7
ENSG00000101882ENST00000652253A0A494C050

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
386472442024From phenotype to mechanism: Prenatal spectrum of NKAP mutation-related disorder and its pathogenesis inducing congenital heart disease.1
386472442024From phenotype to mechanism: Prenatal spectrum of NKAP mutation-related disorder and its pathogenesis inducing congenital heart disease.1
350641122022RNA binding protein NKAP protects glioblastoma cells from ferroptosis by promoting SLC7A11 mRNA splicing in an m(6)A-dependent manner.43
350641122022RNA binding protein NKAP protects glioblastoma cells from ferroptosis by promoting SLC7A11 mRNA splicing in an m(6)A-dependent manner.43
337540522021MARCKS cooperates with NKAP to activate NF-kB signaling in smoke-related lung cancer.18
337540522021MARCKS cooperates with NKAP to activate NF-kB signaling in smoke-related lung cancer.18
320329762020NKAP promotes renal cell carcinoma growth via AKT/mTOR signalling pathway.3
320329762020NKAP promotes renal cell carcinoma growth via AKT/mTOR signalling pathway.3
312776842019NKAP alters tumor immune microenvironment and promotes glioma growth via Notch1 signaling.19
315454742019The oncogenic role of NKAP in the growth and invasion of colon cancer cells.4
315878682019Missense Mutations in NKAP Cause a Disorder of Transcriptional Regulation Characterized by Marfanoid Habitus and Cognitive Impairment.7
312776842019NKAP alters tumor immune microenvironment and promotes glioma growth via Notch1 signaling.19
315454742019The oncogenic role of NKAP in the growth and invasion of colon cancer cells.4
315878682019Missense Mutations in NKAP Cause a Disorder of Transcriptional Regulation Characterized by Marfanoid Habitus and Cognitive Impairment.7
276948842016SUMOylated NKAP is essential for chromosome alignment by anchoring CENP-E to kinetochores.25

Citation

Dessen P

NKAP (NFKB activating protein)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56120/nkap-(nfkb-activating-protein)