PEX11B (peroxisomal biogenesis factor 11 beta)

2016-10-01  

Identity

HGNC
LOCATION
1q21.1
LOCUSID
ALIAS
PEX11-BETA,PEX14B
FUSION GENES

Other Information

Locus ID:

NCBI: 8799
MIM: 603867
HGNC: 8853
Ensembl: ENSG00000131779

Variants:

dbSNP: 8799
ClinVar: 8799
TCGA: ENSG00000131779
COSMIC: PEX11B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000131779ENST00000369306O96011
ENSG00000131779ENST00000369306A0A024R4E7
ENSG00000131779ENST00000428634H7C3V6
ENSG00000131779ENST00000537888O96011

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
PeroxisomeKEGGko04146
PeroxisomeKEGGhsa04146

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
384232772024Two siblings with PEX11B-related peroxisome biogenesis disorder.0
387537622024PPARgamma dependent PEX11beta counteracts the suppressive role of SIRT1 on neural differentiation of HESCs.0
384232772024Two siblings with PEX11B-related peroxisome biogenesis disorder.0
387537622024PPARgamma dependent PEX11beta counteracts the suppressive role of SIRT1 on neural differentiation of HESCs.0
365227962023Genetic defects in peroxisome morphogenesis (Pex11β, dynamin-like protein 1, and nucleoside diphosphate kinase 3) affect docosahexaenoic acid-phospholipid metabolism.6
365227962023Genetic defects in peroxisome morphogenesis (Pex11β, dynamin-like protein 1, and nucleoside diphosphate kinase 3) affect docosahexaenoic acid-phospholipid metabolism.6
356783362022PEX11β and FIS1 cooperate in peroxisome division independently of mitochondrial fission factor.8
356783362022PEX11β and FIS1 cooperate in peroxisome division independently of mitochondrial fission factor.8
311291172019Deciphering the potential involvement of PXMP2 and PEX11B in hydrogen peroxide permeation across the peroxisomal membrane reveals a role for PEX11B in protein sorting.17
311291172019Deciphering the potential involvement of PXMP2 and PEX11B in hydrogen peroxide permeation across the peroxisomal membrane reveals a role for PEX11B in protein sorting.17
281294232017Novel PEX11B Mutations Extend the Peroxisome Biogenesis Disorder 14B Phenotypic Spectrum and Underscore Congenital Cataract as an Early Feature.13
281294232017Novel PEX11B Mutations Extend the Peroxisome Biogenesis Disorder 14B Phenotypic Spectrum and Underscore Congenital Cataract as an Early Feature.13
233082202013Self-interaction of human Pex11pβ during peroxisomal growth and division.16
233082202013Self-interaction of human Pex11pβ during peroxisomal growth and division.16
225819682012A novel defect of peroxisome division due to a homozygous non-sense mutation in the PEX11β gene.50

Citation

Dessen P

PEX11B (peroxisomal biogenesis factor 11 beta)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56126/pex11b-(peroxisomal-biogenesis-factor-11-beta)