CALCB (calcitonin related polypeptide beta)

2016-10-01  

Identity

HGNC
CALCB
LOCATION
11p15.2
LOCUSID
797
ALIAS
CALC2,CGRP-II,CGRP2

Other Information

Locus ID:

NCBI: 797
MIM: 114160
HGNC: 1438
Ensembl: ENSG00000175868

Variants:

dbSNP: 797
ClinVar: 797
TCGA: ENSG00000175868
COSMIC: CALCB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000175868ENST00000324229P10092
ENSG00000175868ENST00000523376E7ESF5
ENSG00000175868ENST00000533448P10092

Expression (GTEx)

0
1
2
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class B/2 (Secretin family receptors)REACTOMER-HSA-373080
Calcitonin-like ligand receptorsREACTOMER-HSA-419812
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (s) signalling eventsREACTOMER-HSA-418555

References

Pubmed IDYearTitleCitations
342348762021CALCB rs3829222 T/T Genotype and Low Expression of CALCB Are High-Risk Factors for Adenoid Cystic Carcinoma of Salivary Gland.2
342348762021CALCB rs3829222 T/T Genotype and Low Expression of CALCB Are High-Risk Factors for Adenoid Cystic Carcinoma of Salivary Gland.2
269671152016Searching for novel ATF4 target genes in human hepatoma cells by microarray analysis.4
269671152016Searching for novel ATF4 target genes in human hepatoma cells by microarray analysis.4
216411132011Keratinocyte expression of calcitonin gene-related peptide β: implications for neuropathic and inflammatory pain mechanisms.64
216411132011Keratinocyte expression of calcitonin gene-related peptide β: implications for neuropathic and inflammatory pain mechanisms.64
190860532009Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.39
191922762009Calcitonin gene-related peptide stimulates proliferation of alveolar epithelial cells.15
190860532009Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.39
191922762009Calcitonin gene-related peptide stimulates proliferation of alveolar epithelial cells.15
157610412005Autocrine/paracrine role of inflammation-mediated calcitonin gene-related peptide and adrenomedullin expression in human adipose tissue.43
157610412005Autocrine/paracrine role of inflammation-mediated calcitonin gene-related peptide and adrenomedullin expression in human adipose tissue.43

Citation

Dessen P

CALCB (calcitonin related polypeptide beta)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56135/calcb-(calcitonin-related-polypeptide-beta)