Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6461
MIM: 600314
HGNC: 10838
Ensembl: ENSG00000107338
Variants:
dbSNP: 6461
ClinVar: 6461
TCGA: ENSG00000107338
COSMIC: SHB
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000107338 | ENST00000377707 | Q15464 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32060095 | 2020 | The Shb scaffold binds the Nck adaptor protein, p120 RasGAP, and Chimaerins and thereby facilitates heterotypic cell segregation by the receptor EphB2. | 3 |
| 32060095 | 2020 | The Shb scaffold binds the Nck adaptor protein, p120 RasGAP, and Chimaerins and thereby facilitates heterotypic cell segregation by the receptor EphB2. | 3 |
| 28982308 | 2017 | Tumor SHB gene expression affects disease characteristics in human acute myeloid leukemia. | 4 |
| 29194461 | 2017 | Evaluation and validation of commercial antibodies for the detection of Shb. | 1 |
| 28982308 | 2017 | Tumor SHB gene expression affects disease characteristics in human acute myeloid leukemia. | 4 |
| 29194461 | 2017 | Evaluation and validation of commercial antibodies for the detection of Shb. | 1 |
| 26489764 | 2016 | The role of the Src Homology-2 domain containing protein B (SHB) in β cells. | 9 |
| 26489764 | 2016 | The role of the Src Homology-2 domain containing protein B (SHB) in β cells. | 9 |
| 16569669 | 2006 | Interaction of SH2-Bbeta with RET is involved in signaling of GDNF-induced neurite outgrowth. | 26 |
| 16630561 | 2006 | SHB and angiogenic factors promote ES cell differentiation to insulin-producing cells. | 4 |
| 16569669 | 2006 | Interaction of SH2-Bbeta with RET is involved in signaling of GDNF-induced neurite outgrowth. | 26 |
| 16630561 | 2006 | SHB and angiogenic factors promote ES cell differentiation to insulin-producing cells. | 4 |
| 11786545 | 2002 | SH2-Bbeta is a Rac-binding protein that regulates cell motility. | 25 |
| 12084069 | 2002 | Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells. | 9 |
| 12200137 | 2002 | IL-2 receptor signaling through the Shb adapter protein in T and NK cells. | 6 |
Citation
Dessen P
SHB (SH2 domain containing adaptor protein B)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56141/shb-(sh2-domain-containing-adaptor-protein-b)
