Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2959
MIM: 189963
HGNC: 4648
Ensembl: ENSG00000137947
Variants:
dbSNP: 2959
ClinVar: 2959
TCGA: ENSG00000137947
COSMIC: GTF2B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000137947 | ENST00000370500 | Q00403 |
| ENSG00000137947 | ENST00000418217 | B1APE2 |
| ENSG00000137947 | ENST00000448623 | B1APE1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34932801 | 2022 | Transcription factor GTF2B regulates AIP protein expression in growth hormone-secreting pituitary adenomas and influences tumor phenotypes. | 7 |
| 35947745 | 2022 | Differential dependencies of human RNA polymerase II promoters on TBP, TAF1, TFIIB and XPB. | 14 |
| 34932801 | 2022 | Transcription factor GTF2B regulates AIP protein expression in growth hormone-secreting pituitary adenomas and influences tumor phenotypes. | 7 |
| 35947745 | 2022 | Differential dependencies of human RNA polymerase II promoters on TBP, TAF1, TFIIB and XPB. | 14 |
| 32417370 | 2020 | Release of Human TFIIB from Actively Transcribing Complexes Is Triggered upon Synthesis of 7- and 9-nt RNAs. | 2 |
| 32417370 | 2020 | Release of Human TFIIB from Actively Transcribing Complexes Is Triggered upon Synthesis of 7- and 9-nt RNAs. | 2 |
| 29158257 | 2018 | Structural dissection of an interaction between transcription initiation and termination factors implicated in promoter-terminator cross-talk. | 9 |
| 29158257 | 2018 | Structural dissection of an interaction between transcription initiation and termination factors implicated in promoter-terminator cross-talk. | 9 |
| 25492609 | 2015 | Association of the winged helix motif of the TFIIEα subunit of TFIIE with either the TFIIEβ subunit or TFIIB distinguishes its functions in transcription. | 2 |
| 26016528 | 2015 | Evaluation of the Intrinsic Zn(II) Affinity of a Cys3His1 Site in the Absence of Protein Folding Effects. | 1 |
| 26284261 | 2015 | In vitro fluorescence studies of transcription factor IIB-DNA interaction. | 1 |
| 25492609 | 2015 | Association of the winged helix motif of the TFIIEα subunit of TFIIE with either the TFIIEβ subunit or TFIIB distinguishes its functions in transcription. | 2 |
| 26016528 | 2015 | Evaluation of the Intrinsic Zn(II) Affinity of a Cys3His1 Site in the Absence of Protein Folding Effects. | 1 |
| 26284261 | 2015 | In vitro fluorescence studies of transcription factor IIB-DNA interaction. | 1 |
| 24441171 | 2014 | A new paradigm for transcription factor TFIIB functionality. | 12 |
Citation
Dessen P
GTF2B (general transcription factor IIB)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56142/gtf2b-(general-transcription-factor-iib)
