TC2N (tandem C2 domains, nuclear)

2016-10-01  

Identity

HGNC
TC2N
LOCATION
14q32.12
LOCUSID
123036
ALIAS
C14orf47,C2CD1,MTAC2D1,TAC2N,Tac2-N
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 123036
HGNC: 19859
Ensembl: ENSG00000165929

Variants:

dbSNP: 123036
ClinVar: 123036
TCGA: ENSG00000165929
COSMIC: TC2N

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165929ENST00000340892Q8N9U0
ENSG00000165929ENST00000360594Q8N9U0
ENSG00000165929ENST00000435962Q8N9U0
ENSG00000165929ENST00000556018Q8N9U0
ENSG00000165929ENST00000556590H0YJ73

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381674402024TC2N inhibits distant metastasis and stemness of breast cancer via blocking fatty acid synthesis.1
381674402024TC2N inhibits distant metastasis and stemness of breast cancer via blocking fatty acid synthesis.1
378396352023TC2N Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma by Targeting the Wnt/β-Catenin Signaling Pathway.1
378396352023TC2N Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma by Targeting the Wnt/β-Catenin Signaling Pathway.1
349253342021TC2N: A Novel Vital Oncogene or Tumor Suppressor Gene In Cancers.5
349253342021TC2N: A Novel Vital Oncogene or Tumor Suppressor Gene In Cancers.5
302543752019TC2N, a novel oncogene, accelerates tumor progression by suppressing p53 signaling pathway in lung cancer.33
314665232019Tac2-N acts as a novel oncogene and promotes tumor metastasis via activation of NF-κB signaling in lung cancer.8
302543752019TC2N, a novel oncogene, accelerates tumor progression by suppressing p53 signaling pathway in lung cancer.33
314665232019Tac2-N acts as a novel oncogene and promotes tumor metastasis via activation of NF-κB signaling in lung cancer.8
210293582011Impact on venous thrombosis risk of newly discovered gene variants associated with FVIII and VWF plasma levels.7
210293582011Impact on venous thrombosis risk of newly discovered gene variants associated with FVIII and VWF plasma levels.7

Citation

Dessen P

TC2N (tandem C2 domains, nuclear)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56170/tc2n-(tandem-c2-domains-nuclear)