Identity
HGNC
LOCATION
4p16.3
LOCUSID
ALIAS
CPX-I,CPX1,DEE63,EIEE63
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10815
MIM: 605032
HGNC: 2309
Ensembl: ENSG00000168993
Variants:
dbSNP: 10815
ClinVar: 10815
TCGA: ENSG00000168993
COSMIC: CPLX1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000168993 | ENST00000304062 | O14810 |
| ENSG00000168993 | ENST00000504062 | D6RAG3 |
| ENSG00000168993 | ENST00000505203 | D6RI11 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32401194 | 2020 | Synergistic roles of Synaptotagmin-1 and complexin in calcium-regulated neuronal exocytosis. | 22 |
| 32401194 | 2020 | Synergistic roles of Synaptotagmin-1 and complexin in calcium-regulated neuronal exocytosis. | 22 |
| 27866231 | 2017 | Presynaptic proteins complexin-I and complexin-II differentially influence cognitive function in early and late stages of Alzheimer's disease. | 21 |
| 28108469 | 2017 | Blood RNA biomarkers in prodromal PARK4 and rapid eye movement sleep behavior disorder show role of complexin 1 loss for risk of Parkinson's disease. | 12 |
| 28422131 | 2017 | Variants in CPLX1 in two families with autosomal-recessive severe infantile myoclonic epilepsy and ID. | 18 |
| 29118371 | 2017 | Genetic association analysis of microRNA137 and its target complex 1 with schizophrenia in Han Chinese. | 2 |
| 27866231 | 2017 | Presynaptic proteins complexin-I and complexin-II differentially influence cognitive function in early and late stages of Alzheimer's disease. | 21 |
| 28108469 | 2017 | Blood RNA biomarkers in prodromal PARK4 and rapid eye movement sleep behavior disorder show role of complexin 1 loss for risk of Parkinson's disease. | 12 |
| 28422131 | 2017 | Variants in CPLX1 in two families with autosomal-recessive severe infantile myoclonic epilepsy and ID. | 18 |
| 29118371 | 2017 | Genetic association analysis of microRNA137 and its target complex 1 with schizophrenia in Han Chinese. | 2 |
| 26577184 | 2016 | Increased complexin-1 and decreased miR-185 expression levels in Behçet's disease with and without neurological involvement. | 4 |
| 26577184 | 2016 | Increased complexin-1 and decreased miR-185 expression levels in Behçet's disease with and without neurological involvement. | 4 |
| 25831964 | 2015 | Re-visiting the trans insertion model for complexin clamping. | 24 |
| 26245303 | 2015 | Complexins: small but capable. | 34 |
| 26603934 | 2015 | Carboxypeptidase X-1 (CPX-1) is a secreted collagen-binding glycoprotein. | 11 |
Citation
Dessen P
CPLX1 (complexin 1)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56183/cplx1-(complexin-1)
