SGSM1 (small G protein signaling modulator 1)

2016-10-01  

Identity

HGNC
LOCATION
22q11.23
LOCUSID
ALIAS
RUTBC2
FUSION GENES

Other Information

Locus ID:

NCBI: 129049
MIM: 611417
HGNC: 29410
Ensembl: ENSG00000167037

Variants:

dbSNP: 129049
ClinVar: 129049
TCGA: ENSG00000167037
COSMIC: SGSM1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167037ENST00000400358Q2NKQ1
ENSG00000167037ENST00000400359Q2NKQ1
ENSG00000167037ENST00000610372A0A087X241

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
354845112022Prognostic biomarker SGSM1 and its correlation with immune infiltration in gliomas.3
354845112022Prognostic biomarker SGSM1 and its correlation with immune infiltration in gliomas.3
305735202019Hypermethylation of SHISA3 Promotes Nasopharyngeal Carcinoma Metastasis by Reducing SGSM1 Stability.25
305735202019Hypermethylation of SHISA3 Promotes Nasopharyngeal Carcinoma Metastasis by Reducing SGSM1 Stability.25
226374802012RUTBC2 protein, a Rab9A effector and GTPase-activating protein for Rab36.18
226374802012RUTBC2 protein, a Rab9A effector and GTPase-activating protein for Rab36.18
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105
175098192007Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway.27
175098192007Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway.27

Citation

Dessen P

SGSM1 (small G protein signaling modulator 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56193/gene-fusions/js/welcome