Identity
HGNC
LOCATION
3p25.2
LOCUSID
ALIAS
HSPC070,RNF62
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23609
MIM: 608426
HGNC: 7113
Ensembl: ENSG00000075975
Variants:
dbSNP: 23609
ClinVar: 23609
TCGA: ENSG00000075975
COSMIC: MKRN2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000075975 | ENST00000170447 | Q9H000 |
| ENSG00000075975 | ENST00000411987 | Q9H000 |
| ENSG00000075975 | ENST00000448482 | C9J494 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38753876 | 2024 | Identifying cellular RNA-binding proteins during infection uncovers a role for MKRN2 in influenza mRNA trafficking. | 1 |
| 38753876 | 2024 | Identifying cellular RNA-binding proteins during infection uncovers a role for MKRN2 in influenza mRNA trafficking. | 1 |
| 36938725 | 2023 | MKRN1/2 serve as tumor suppressors in renal clear cell carcinoma by regulating the expression of p53. | 1 |
| 37528788 | 2023 | [Overexpression of MKRN2 Inhibits the Growth of Ovarian Cancer Cells]. | 0 |
| 36938725 | 2023 | MKRN1/2 serve as tumor suppressors in renal clear cell carcinoma by regulating the expression of p53. | 1 |
| 37528788 | 2023 | [Overexpression of MKRN2 Inhibits the Growth of Ovarian Cancer Cells]. | 0 |
| 31814304 | 2020 | Integrated analysis of exosomal lncRNA and mRNA expression profiles reveals the involvement of lnc-MKRN2-42:1 in the pathogenesis of Parkinson's disease. | 38 |
| 32560817 | 2020 | Ubiquitination of IGF2BP3 by E3 ligase MKRN2 regulates the proliferation and migration of human neuroblastoma SHSY5Y cells. | 12 |
| 31814304 | 2020 | Integrated analysis of exosomal lncRNA and mRNA expression profiles reveals the involvement of lnc-MKRN2-42:1 in the pathogenesis of Parkinson's disease. | 38 |
| 32560817 | 2020 | Ubiquitination of IGF2BP3 by E3 ligase MKRN2 regulates the proliferation and migration of human neuroblastoma SHSY5Y cells. | 12 |
| 30103781 | 2018 | MKRN2 inhibits migration and invasion of non-small-cell lung cancer by negatively regulating the PI3K/Akt pathway. | 27 |
| 30103781 | 2018 | MKRN2 inhibits migration and invasion of non-small-cell lung cancer by negatively regulating the PI3K/Akt pathway. | 27 |
| 28378844 | 2017 | MKRN2 is a novel ubiquitin E3 ligase for the p65 subunit of NF-κB and negatively regulates inflammatory responses. | 31 |
| 28378844 | 2017 | MKRN2 is a novel ubiquitin E3 ligase for the p65 subunit of NF-κB and negatively regulates inflammatory responses. | 31 |
| 24675897 | 2014 | Ubiquitous expression of MAKORIN-2 in normal and malignant hematopoietic cells and its growth promoting activity. | 10 |
Citation
Dessen P
MKRN2 (makorin ring finger protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56213/mkrn2-(makorin-ring-finger-protein-2)
