C2CD5 (C2 calcium dependent domain containing 5)

2016-10-01  

Identity

HGNC
C2CD5
LOCATION
12p12.1
LOCUSID
9847
ALIAS
CDP138,KIAA0528
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9847
MIM: 618044
HGNC: 29062
Ensembl: ENSG00000111731

Variants:

dbSNP: 9847
ClinVar: 9847
TCGA: ENSG00000111731
COSMIC: C2CD5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000111731ENST00000333957Q86YS7
ENSG00000111731ENST00000396028Q86YS7
ENSG00000111731ENST00000446597Q86YS7
ENSG00000111731ENST00000535555H0YGU7
ENSG00000111731ENST00000536386Q86YS7
ENSG00000111731ENST00000539615H0YFC4
ENSG00000111731ENST00000542676Q86YS7
ENSG00000111731ENST00000542683H0YFE9
ENSG00000111731ENST00000545552Q86YS7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Translocation of GLUT4 to the plasma membraneREACTOMER-HSA-1445148

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
306515362019Regulation of in vivo dynein force production by CDK5 and 14-3-3ε and KIAA0528.9
306515362019Regulation of in vivo dynein force production by CDK5 and 14-3-3ε and KIAA0528.9
288802652017CDP138 silencing inhibits TGF-β/Smad signaling to impair radioresistance and metastasis via GDF15 in lung cancer.20
288802652017CDP138 silencing inhibits TGF-β/Smad signaling to impair radioresistance and metastasis via GDF15 in lung cancer.20

Citation

Dessen P

C2CD5 (C2 calcium dependent domain containing 5)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56216/c2cd5-(c2-calcium-dependent-domain-containing-5)