Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6809
MIM: 600876
HGNC: 11438
Ensembl: ENSG00000166900
Variants:
dbSNP: 6809
ClinVar: 6809
TCGA: ENSG00000166900
COSMIC: STX3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38014487 | 2023 | Increased STX3 transcript and protein levels were associated with poor prognosis in two independent cohorts of esophageal squamous cell carcinoma patients. | 1 |
| 38014487 | 2023 | Increased STX3 transcript and protein levels were associated with poor prognosis in two independent cohorts of esophageal squamous cell carcinoma patients. | 1 |
| 33974130 | 2021 | Pathogenic STX3 variants affecting the retinal and intestinal transcripts cause an early-onset severe retinal dystrophy in microvillus inclusion disease subjects. | 12 |
| 33974130 | 2021 | Pathogenic STX3 variants affecting the retinal and intestinal transcripts cause an early-onset severe retinal dystrophy in microvillus inclusion disease subjects. | 12 |
| 31201948 | 2019 | Interaction networks of Weibel-Palade body regulators syntaxin-3 and syntaxin binding protein 5 in endothelial cells. | 3 |
| 31201948 | 2019 | Interaction networks of Weibel-Palade body regulators syntaxin-3 and syntaxin binding protein 5 in endothelial cells. | 3 |
| 29408595 | 2018 | STX3 represses the stability of the tumor suppressor PTEN to activate the PI3K-Akt-mTOR signaling and promotes the growth of breast cancer cells. | 14 |
| 29475951 | 2018 | Soluble syntaxin 3 functions as a transcriptional regulator. | 9 |
| 29880488 | 2018 | Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells. | 22 |
| 29408595 | 2018 | STX3 represses the stability of the tumor suppressor PTEN to activate the PI3K-Akt-mTOR signaling and promotes the growth of breast cancer cells. | 14 |
| 29475951 | 2018 | Soluble syntaxin 3 functions as a transcriptional regulator. | 9 |
| 29880488 | 2018 | Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells. | 22 |
| 25358429 | 2015 | Autosomal recessive congenital cataract, intellectual disability phenotype linked to STX3 in a consanguineous Tunisian family. | 11 |
| 25548252 | 2015 | An essential role of syntaxin 3 protein for granule exocytosis and secretion of IL-1α, IL-1β, IL-12b, and CCL4 from differentiated HL-60 cells. | 19 |
| 25583387 | 2015 | Human cytomegalovirus miR-US33-5p inhibits viral DNA synthesis and viral replication by down-regulating expression of the host Syntaxin3. | 12 |
Citation
Dessen P
STX3 (syntaxin 3)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56217/stx3-(syntaxin-3)
