Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57829
MIM: 613514
HGNC: 15770
Ensembl: ENSG00000116996
Variants:
dbSNP: 57829
ClinVar: 57829
TCGA: ENSG00000116996
COSMIC: ZP4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000116996 | ENST00000366570 | Q12836 |
| ENSG00000116996 | ENST00000611898 | Q12836 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Reproduction | REACTOME | R-HSA-1474165 |
| Fertilization | REACTOME | R-HSA-1187000 |
| Interaction With The Zona Pellucida | REACTOME | R-HSA-1300644 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33461974 | 2022 | Mutations in ZP4 are associated with abnormal zona pellucida and female infertility. | 8 |
| 33461974 | 2022 | Mutations in ZP4 are associated with abnormal zona pellucida and female infertility. | 8 |
| 32569527 | 2020 | Zona Pellucida Proteins, Fibrils, and Matrix. | 24 |
| 32569527 | 2020 | Zona Pellucida Proteins, Fibrils, and Matrix. | 24 |
| 30298508 | 2018 | [Association of ZP4 gene polymorphism with primary open-angle glaucoma in an ethnic Chinese population from Sichuan province]. | 1 |
| 30298508 | 2018 | [Association of ZP4 gene polymorphism with primary open-angle glaucoma in an ethnic Chinese population from Sichuan province]. | 1 |
| 25740067 | 2015 | Study on the zona pellucida 4 (ZP4) gene sequence and its expression in the ovaries of patients with polycystic ovary syndrome. | 8 |
| 25740067 | 2015 | Study on the zona pellucida 4 (ZP4) gene sequence and its expression in the ovaries of patients with polycystic ovary syndrome. | 8 |
| 21173071 | 2011 | Human ZP4 is not sufficient for taxon-specific sperm recognition of the zona pellucida in transgenic mice. | 15 |
| 21173071 | 2011 | Human ZP4 is not sufficient for taxon-specific sperm recognition of the zona pellucida in transgenic mice. | 15 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 19004505 | 2009 | DNA vaccine encoding chimeric protein encompassing epitopes of human ZP3 and ZP4: immunogenicity and characterization of antibodies. | 5 |
| 19625618 | 2009 | Three susceptible loci associated with primary open-angle glaucoma identified by genome-wide association study in a Japanese population. | 48 |
| 19626040 | 2009 | Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis. | 3 |
Citation
Dessen P
ZP4 (zona pellucida glycoprotein 4)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56229/zp4-(zona-pellucida-glycoprotein-4)
