SIDT2 (SID1 transmembrane family member 2)

2016-10-01  

Identity

HGNC
SIDT2
LOCATION
11q23.3
LOCUSID
51092
ALIAS
CGI-40
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51092
MIM: 617551
HGNC: 24272
Ensembl: ENSG00000149577

Variants:

dbSNP: 51092
ClinVar: 51092
TCGA: ENSG00000149577
COSMIC: SIDT2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000149577ENST00000278951C9JBG5
ENSG00000149577ENST00000324225Q8NBJ9
ENSG00000149577ENST00000431081F5H8L4
ENSG00000149577ENST00000524842E9PPN9
ENSG00000149577ENST00000525478H0YEI3
ENSG00000149577ENST00000531353E9PME7
ENSG00000149577ENST00000532062G3V172
ENSG00000149577ENST00000532960E9PMC3
ENSG00000149577ENST00000620360Q8NBJ9
ENSG00000149577ENST00000628876C9JBG5

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
366782412023Interaction between SIDT2 and ABCA1 Variants with Nutrients on HDL-c Levels in Mexican Adults.3
372022012023[Lysosomal membrane protein Sidt2 knockout induces apoptosis of human hepatocytes in vitro independent of the autophagy-lysosomal pathway].0
373220072023Structural insight into the human SID1 transmembrane family member 2 reveals its lipid hydrolytic activity.10
378305672023SIDT2 Associates with Apolipoprotein A1 (ApoA1) and Facilitates ApoA1 Secretion in Hepatocytes.3
366782412023Interaction between SIDT2 and ABCA1 Variants with Nutrients on HDL-c Levels in Mexican Adults.3
372022012023[Lysosomal membrane protein Sidt2 knockout induces apoptosis of human hepatocytes in vitro independent of the autophagy-lysosomal pathway].0
373220072023Structural insight into the human SID1 transmembrane family member 2 reveals its lipid hydrolytic activity.10
378305672023SIDT2 Associates with Apolipoprotein A1 (ApoA1) and Facilitates ApoA1 Secretion in Hepatocytes.3
348005822022Pathology-associated change in levels and localization of SIDT2 in postmortem brains of Parkinson's disease and dementia with Lewy bodies patients.7
348005822022Pathology-associated change in levels and localization of SIDT2 in postmortem brains of Parkinson's disease and dementia with Lewy bodies patients.7
342334762021Genome-Wide Association Study Identifies a Functional SIDT2 Variant Associated With HDL-C (High-Density Lipoprotein Cholesterol) Levels and Premature Coronary Artery Disease.10
345497122021[Lysosomal membrane protein Sidt2 deletion impairs autophagy in human hepatocytes].1
347818152021Long non-coding RNA LIFR-AS1 suppressed the proliferation, angiogenesis, migration and invasion of papillary thyroid cancer cells via the miR-31-5p/SIDT2 axis.9
342334762021Genome-Wide Association Study Identifies a Functional SIDT2 Variant Associated With HDL-C (High-Density Lipoprotein Cholesterol) Levels and Premature Coronary Artery Disease.10
345497122021[Lysosomal membrane protein Sidt2 deletion impairs autophagy in human hepatocytes].1

Citation

Dessen P

SIDT2 (SID1 transmembrane family member 2)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56230/sidt2-(sid1-transmembrane-family-member-2)