Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6810
MIM: 186591
HGNC: 11439
Ensembl: ENSG00000103496
Variants:
dbSNP: 6810
ClinVar: 6810
TCGA: ENSG00000103496
COSMIC: STX4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA450921 | phenprocoumon | Chemical | ClinicalAnnotation | associated | PD | 21063236 | |
| PA451906 | warfarin | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36355422 | 2023 | Syntaxin 4 is essential for hearing in human and zebrafish. | 2 |
| 37885878 | 2023 | Syntaxin-4 and SNAP23 are involved in neutrophil degranulation, but not in the release of mitochondrial DNA during NET formation. | 0 |
| 38136609 | 2023 | Phosphorylation of Syntaxin 4 by the Insulin Receptor Drives Exocytic SNARE Complex Formation to Deliver GLUT4 to the Cell Surface. | 0 |
| 36355422 | 2023 | Syntaxin 4 is essential for hearing in human and zebrafish. | 2 |
| 37885878 | 2023 | Syntaxin-4 and SNAP23 are involved in neutrophil degranulation, but not in the release of mitochondrial DNA during NET formation. | 0 |
| 38136609 | 2023 | Phosphorylation of Syntaxin 4 by the Insulin Receptor Drives Exocytic SNARE Complex Formation to Deliver GLUT4 to the Cell Surface. | 0 |
| 34482824 | 2021 | Up-regulation expression and prognostic significance of Syntaxin4 in kidney renal clear cell carcinoma. | 2 |
| 34482824 | 2021 | Up-regulation expression and prognostic significance of Syntaxin4 in kidney renal clear cell carcinoma. | 2 |
| 29358308 | 2018 | β-adrenoceptor activation increased VAMP-2 and syntaxin-4 in secretory granules are involved in protein secretion of submandibular gland through the PKA/F-actin pathway. | 1 |
| 29896202 | 2018 | Nitric Oxide Generated by Tumor-Associated Macrophages Is Responsible for Cancer Resistance to Cisplatin and Correlated With Syntaxin 4 and Acid Sphingomyelinase Inhibition. | 54 |
| 29358308 | 2018 | β-adrenoceptor activation increased VAMP-2 and syntaxin-4 in secretory granules are involved in protein secretion of submandibular gland through the PKA/F-actin pathway. | 1 |
| 29896202 | 2018 | Nitric Oxide Generated by Tumor-Associated Macrophages Is Responsible for Cancer Resistance to Cisplatin and Correlated With Syntaxin 4 and Acid Sphingomyelinase Inhibition. | 54 |
| 28524818 | 2017 | Fluorescence Lifetime Imaging Microscopy reveals rerouting of SNARE trafficking driving dendritic cell activation. | 10 |
| 28624237 | 2017 | Identification of syntaxin 4 as an essential factor for the hepatitis C virus life cycle. | 7 |
| 28798239 | 2017 | Interaction of Munc18c and syntaxin4 facilitates invadopodium formation and extracellular matrix invasion of tumor cells. | 9 |
Citation
Dessen P
STX4 (syntaxin 4)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56250/stx4-(syntaxin-4)
