ECSCR (endothelial cell surface expressed chemotaxis and apoptosis regulator)

2016-10-01  

Identity

HGNC
LOCATION
5q31.2
LOCUSID
ALIAS
ARIA,ECSM2
FUSION GENES

Other Information

Locus ID:

NCBI: 641700
MIM: 615736
HGNC: 35454
Ensembl: ENSG00000249751

Variants:

dbSNP: 641700
ClinVar: 641700
TCGA: ENSG00000249751
COSMIC: ECSCR

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000249751ENST00000618155Q19T08

Expression (GTEx)

0
50
100
150

References

Pubmed IDYearTitleCitations
269560512016Biomarkers of evasive resistance predict disease progression in cancer patients treated with antiangiogenic therapies.9
269560512016Biomarkers of evasive resistance predict disease progression in cancer patients treated with antiangiogenic therapies.9
233931312013Endothelial cell-specific chemotaxis receptor (ECSCR) enhances vascular endothelial growth factor (VEGF) receptor-2/kinase insert domain receptor (KDR) activation and promotes proteolysis of internalized KDR.8
233931312013Endothelial cell-specific chemotaxis receptor (ECSCR) enhances vascular endothelial growth factor (VEGF) receptor-2/kinase insert domain receptor (KDR) activation and promotes proteolysis of internalized KDR.8
231475652012Identification of novel splice variants and exons of human endothelial cell-specific chemotaxic regulator (ECSCR) by bioinformatics analysis.3
231475652012Identification of novel splice variants and exons of human endothelial cell-specific chemotaxic regulator (ECSCR) by bioinformatics analysis.3
217205472011Endothelial cell-specific molecule 2 (ECSM2) localizes to cell-cell junctions and modulates bFGF-directed cell migration via the ERK-FAK pathway.11
217205472011Endothelial cell-specific molecule 2 (ECSM2) localizes to cell-cell junctions and modulates bFGF-directed cell migration via the ERK-FAK pathway.11
192407912009Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis.26
192677802009Endothelial cell-specific molecule 2 (ECSM2) modulates actin remodeling and epidermal growth factor receptor signaling.10
194168532009Identification of ARIA regulating endothelial apoptosis and angiogenesis by modulating proteasomal degradation of cIAP-1 and cIAP-2.16
192407912009Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis.26
192677802009Endothelial cell-specific molecule 2 (ECSM2) modulates actin remodeling and epidermal growth factor receptor signaling.10
194168532009Identification of ARIA regulating endothelial apoptosis and angiogenesis by modulating proteasomal degradation of cIAP-1 and cIAP-2.16
185565732008ECSM2, an endothelial specific filamin a binding protein that mediates chemotaxis.19

Citation

Dessen P

ECSCR (endothelial cell surface expressed chemotaxis and apoptosis regulator)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56251/ecscr-(endothelial-cell-surface-expressed-chemotaxis-and-apoptosis-regulator)