CRISP1 (cysteine rich secretory protein 1)

2016-10-01  

Identity

HGNC
CRISP1
LOCATION
6p12.3
LOCUSID
167
ALIAS
AEGL1,ARP,CRISP-1,HEL-S-57,HSCRISP1D,HSCRISP1G,HUMARP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 167
MIM: 601193
HGNC: 304
Ensembl: ENSG00000124812

Variants:

dbSNP: 167
ClinVar: 167
TCGA: ENSG00000124812
COSMIC: CRISP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000124812ENST00000329411P54107
ENSG00000124812ENST00000335847P54107
ENSG00000124812ENST00000335847A0A0K0K1I1
ENSG00000124812ENST00000505118P54107
ENSG00000124812ENST00000505118A0A0K0K1I1
ENSG00000124812ENST00000507853P54107

Expression (GTEx)

0
1
2
3
4
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
337508402021The less conserved metal-binding site in human CRISP1 remains sensitive to zinc ions to permit protein oligomerization.2
337508402021The less conserved metal-binding site in human CRISP1 remains sensitive to zinc ions to permit protein oligomerization.2
243342452014Human fertilization: epididymal hCRISP1 mediates sperm-zona pellucida binding through its interaction with ZP3.16
243342452014Human fertilization: epididymal hCRISP1 mediates sperm-zona pellucida binding through its interaction with ZP3.16
239875192013Cysteine-rich secretory protein 1 in seminal plasma: potential biomarker for the distinction between obstructive and nonobstructive azoospermia.6
239875192013Cysteine-rich secretory protein 1 in seminal plasma: potential biomarker for the distinction between obstructive and nonobstructive azoospermia.6
203789252010Vasectomy affects cysteine-rich secretory protein expression along the human epididymis and its association with ejaculated spermatozoa following vasectomy surgical reversal.3
203789252010Vasectomy affects cysteine-rich secretory protein expression along the human epididymis and its association with ejaculated spermatozoa following vasectomy surgical reversal.3

Citation

Dessen P

CRISP1 (cysteine rich secretory protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56257/crisp1-(cysteine-rich-secretory-protein-1)