LRRN1 (leucine rich repeat neuronal 1)

2016-10-01  

Identity

HGNC
LOCATION
3p26.2
LOCUSID
ALIAS
FIGLER3,NLRR-1

Other Information

Locus ID:

NCBI: 57633
HGNC: 20980
Ensembl: ENSG00000175928

Variants:

dbSNP: 57633
ClinVar: 57633
TCGA: ENSG00000175928
COSMIC: LRRN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000175928ENST00000319331Q6UXK5

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
388625132024Whole-genome sequencing identifies variants in ANK1, LRRN1, HAS1, and other genes and regulatory regions for stroke in type 1 diabetes.0
388625132024Whole-genome sequencing identifies variants in ANK1, LRRN1, HAS1, and other genes and regulatory regions for stroke in type 1 diabetes.0
310875252019Leucine-rich repeat neuronal protein-1 suppresses apoptosis of gastric cancer cells through regulation of Fas/FasL.10
310875252019Leucine-rich repeat neuronal protein-1 suppresses apoptosis of gastric cancer cells through regulation of Fas/FasL.10
298930542018Leucine-Rich Repeat Neuronal Protein 1 Regulates Differentiation of Embryonic Stem Cells by Post-Translational Modifications of Pluripotency Factors.8
298930542018Leucine-Rich Repeat Neuronal Protein 1 Regulates Differentiation of Embryonic Stem Cells by Post-Translational Modifications of Pluripotency Factors.8
276043202016Neuronal leucine-rich repeat 1 negatively regulates anaplastic lymphoma kinase in neuroblastoma.4
276043202016Neuronal leucine-rich repeat 1 negatively regulates anaplastic lymphoma kinase in neuroblastoma.4
206782492010Polymorphisms in leucine-rich repeat genes are associated with autism spectrum disorder susceptibility in populations of European ancestry.25
206782492010Polymorphisms in leucine-rich repeat genes are associated with autism spectrum disorder susceptibility in populations of European ancestry.25
185919372008N-MYC promotes cell proliferation through a direct transactivation of neuronal leucine-rich repeat protein-1 (NLRR1) gene in neuroblastoma.18
185919372008N-MYC promotes cell proliferation through a direct transactivation of neuronal leucine-rich repeat protein-1 (NLRR1) gene in neuroblastoma.18

Citation

Dessen P

LRRN1 (leucine rich repeat neuronal 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56264/lrrn1-(leucine-rich-repeat-neuronal-1)