Identity
HGNC
LOCATION
1q23.1
LOCUSID
ALIAS
F2771,SCAP,TSAD,VRAP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9047
MIM: 604514
HGNC: 10821
Ensembl: ENSG00000027869
Variants:
dbSNP: 9047
ClinVar: 9047
TCGA: ENSG00000027869
COSMIC: SH2D2A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000027869 | ENST00000368198 | Q9NP31 |
| ENSG00000027869 | ENST00000368199 | Q9NP31 |
| ENSG00000027869 | ENST00000392306 | Q9NP31 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37315471 | 2023 | Downregulation of lncRNA XIST may promote Th17 differentiation through KDM6A-TSAd pathway in neuromyelitis optica spectrum disorders. | 3 |
| 37315471 | 2023 | Downregulation of lncRNA XIST may promote Th17 differentiation through KDM6A-TSAd pathway in neuromyelitis optica spectrum disorders. | 3 |
| 33046503 | 2020 | TSAd Plays a Major Role in Myo9b-Mediated Suppression of Malignant Pleural Effusion by Regulating T(H)1/T(H)17 Cell Response. | 6 |
| 33046503 | 2020 | TSAd Plays a Major Role in Myo9b-Mediated Suppression of Malignant Pleural Effusion by Regulating T(H)1/T(H)17 Cell Response. | 6 |
| 31484725 | 2019 | The SH3 domains of the protein kinases ITK and LCK compete for adjacent sites on T cell-specific adapter protein. | 4 |
| 31484725 | 2019 | The SH3 domains of the protein kinases ITK and LCK compete for adjacent sites on T cell-specific adapter protein. | 4 |
| 27896837 | 2017 | CD6 and Linker of Activated T Cells are Potential Interaction Partners for T Cell-Specific Adaptor Protein. | 10 |
| 27896837 | 2017 | CD6 and Linker of Activated T Cells are Potential Interaction Partners for T Cell-Specific Adaptor Protein. | 10 |
| 26163016 | 2015 | T cell specific adaptor protein (TSAd) promotes interaction of Nck with Lck and SLP-76 in T cells. | 8 |
| 26163016 | 2015 | T cell specific adaptor protein (TSAd) promotes interaction of Nck with Lck and SLP-76 in T cells. | 8 |
| 24910151 | 2014 | Expression of the T cell-specific adapter protein in human tissues. | 1 |
| 25492967 | 2014 | The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192. | 12 |
| 24910151 | 2014 | Expression of the T cell-specific adapter protein in human tissues. | 1 |
| 25492967 | 2014 | The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192. | 12 |
| 21696499 | 2011 | Polymorphism of CD1 and SH2D2A genes in inflammatory neuropathies. | 7 |
Citation
Dessen P
SH2D2A (SH2 domain containing 2A)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56286/sh2d2a-(sh2-domain-containing-2a)
