Identity
HGNC
LOCATION
11q13.1
LOCUSID
ALIAS
CATSPER,SPGF7
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 117144
MIM: 606389
HGNC: 17116
Ensembl: ENSG00000175294
Variants:
dbSNP: 117144
ClinVar: 117144
TCGA: ENSG00000175294
COSMIC: CATSPER1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000175294 | ENST00000312106 | Q8NEC5 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Reproduction | REACTOME | R-HSA-1474165 |
| Fertilization | REACTOME | R-HSA-1187000 |
| Sperm Motility And Taxes | REACTOME | R-HSA-1300642 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38335261 | 2024 | Both protein and non-protein components in extracellular vesicles of human seminal plasma improve human sperm function via CatSper-mediated calcium signaling. | 1 |
| 38366201 | 2024 | Flagellar pH homeostasis mediated by Na+/H+ exchangers regulates human sperm functions through coupling with CatSper and KSper activation. | 1 |
| 38335261 | 2024 | Both protein and non-protein components in extracellular vesicles of human seminal plasma improve human sperm function via CatSper-mediated calcium signaling. | 1 |
| 38366201 | 2024 | Flagellar pH homeostasis mediated by Na+/H+ exchangers regulates human sperm functions through coupling with CatSper and KSper activation. | 1 |
| 33456575 | 2021 | Roles of CatSper channels in the pathogenesis of asthenozoospermia and the therapeutic effects of acupuncture-like treatment on asthenozoospermia. | 14 |
| 34440724 | 2021 | CRISP2, CATSPER1 and PATE1 Expression in Human Asthenozoospermic Semen. | 7 |
| 33456575 | 2021 | Roles of CatSper channels in the pathogenesis of asthenozoospermia and the therapeutic effects of acupuncture-like treatment on asthenozoospermia. | 14 |
| 34440724 | 2021 | CRISP2, CATSPER1 and PATE1 Expression in Human Asthenozoospermic Semen. | 7 |
| 32712386 | 2020 | CatSper: The complex main gate of calcium entry in mammalian spermatozoa. | 25 |
| 32712386 | 2020 | CatSper: The complex main gate of calcium entry in mammalian spermatozoa. | 25 |
| 30203545 | 2019 | Tyrosine phosphorylation signaling regulates Ca(2+) entry by affecting intracellular pH during human sperm capacitation. | 15 |
| 30203545 | 2019 | Tyrosine phosphorylation signaling regulates Ca(2+) entry by affecting intracellular pH during human sperm capacitation. | 15 |
| 30017233 | 2018 | Human CATSPER1 Promoter Is Regulated by CREB1 and CREMτ Transcriptional Factors In Vitro. | 4 |
| 30379860 | 2018 | Regulation of CATSPER1 expression by the testis-determining gene SRY. | 3 |
| 30017233 | 2018 | Human CATSPER1 Promoter Is Regulated by CREB1 and CREMτ Transcriptional Factors In Vitro. | 4 |
Citation
Dessen P
CATSPER1 (cation channel sperm associated 1)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56291/catsper1-(cation-channel-sperm-associated-1)
