SDR16C5 (short chain dehydrogenase/reductase family 16C member 5)

2016-10-01  

Identity

HGNC
SDR16C5
LOCATION
8q12.1
LOCUSID
195814
ALIAS
EPHD-2,RDH#2,RDH-E2,RDHE2,retSDR2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 195814
MIM: 608989
HGNC: 30311
Ensembl: ENSG00000170786

Variants:

dbSNP: 195814
ClinVar: 195814
TCGA: ENSG00000170786
COSMIC: SDR16C5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170786ENST00000303749Q8N3Y7
ENSG00000170786ENST00000396721Q8N3Y7
ENSG00000170786ENST00000522671G3V145

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Retinol metabolismKEGGko00830
Retinol metabolismKEGGhsa00830
Signal TransductionREACTOMER-HSA-162582
Signaling by Retinoic AcidREACTOMER-HSA-5362517
RA biosynthesis pathwayREACTOMER-HSA-5365859

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
388981372024LRG1 and SDR16C5 protein expressions differ according to HPV status in oropharyngeal squamous cell carcinoma.0
388981372024LRG1 and SDR16C5 protein expressions differ according to HPV status in oropharyngeal squamous cell carcinoma.0
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
205466122010The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.28
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
205466122010The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.28
154573462004hRDH-E2 gene polymorphisms, variable transcriptional start sites, and psoriasis.3
154573462004hRDH-E2 gene polymorphisms, variable transcriptional start sites, and psoriasis.3
123724102002Identification of the hRDH-E2 gene, a novel member of the SDR family, and its increased expression in psoriatic lesion.8
123724102002Identification of the hRDH-E2 gene, a novel member of the SDR family, and its increased expression in psoriatic lesion.8

Citation

Dessen P

SDR16C5 (short chain dehydrogenase/reductase family 16C member 5)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56294/sdr16c5-(short-chain-dehydrogenase-reductase-family-16c-member-5)