DAGLB (diacylglycerol lipase beta)

2016-10-01  

Identity

HGNC
DAGLB
LOCATION
7p22.1
LOCUSID
221955
ALIAS
DAGLBETA,KCCR13L
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 221955
MIM: 614016
HGNC: 28923
Ensembl: ENSG00000164535

Variants:

dbSNP: 221955
ClinVar: 221955
TCGA: ENSG00000164535
COSMIC: DAGLB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164535ENST00000297056Q8NCG7
ENSG00000164535ENST00000425398Q8NCG7
ENSG00000164535ENST00000432248C9JA85
ENSG00000164535ENST00000436575E7ET49
ENSG00000164535ENST00000454738F8WBN0

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Retrograde endocannabinoid signalingKEGGhsa04723
Retrograde endocannabinoid signalingKEGGko04723
HemostasisREACTOMER-HSA-109582
Platelet activation, signaling and aggregationREACTOMER-HSA-76002
Effects of PIP2 hydrolysisREACTOMER-HSA-114508
Arachidonate production from DAGREACTOMER-HSA-426048
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (q) signalling eventsREACTOMER-HSA-416476
Gastrin-CREB signalling pathway via PKC and MAPKREACTOMER-HSA-881907
Aldosterone synthesis and secretionKEGGhsa04925
Aldosterone synthesis and secretionKEGGko04925

References

Pubmed IDYearTitleCitations
146100532003Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain.308
294761672018A novel variant associated with HDL-C levels by modifying DAGLB expression levels: An annotation-based genome-wide association study.3
271157112016Assay and Inhibition of the Purified Catalytic Domain of Diacylglycerol Lipase Beta.0

Citation

Dessen P

DAGLB (diacylglycerol lipase beta)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56298/daglb-(diacylglycerol-lipase-beta)