PDXP (pyridoxal phosphatase)

2016-10-01  

Identity

HGNC
LOCATION
22q13.1
LOCUSID
ALIAS
CIN,PLP,dJ37E16.5

Other Information

Locus ID:

NCBI: 57026
MIM: 609246
HGNC: 30259
Ensembl: ENSG00000241360

Variants:

dbSNP: 57026
ClinVar: 57026
TCGA: ENSG00000241360
COSMIC: PDXP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000241360ENST00000215904Q96GD0
ENSG00000241360ENST00000215904A0A024R1I3
ENSG00000241360ENST00000403251B1AHD3

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Vitamin B6 metabolismKEGGko00750
Vitamin B6 metabolismKEGGhsa00750
Metabolic pathwaysKEGGhsa01100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
297241932018Chronophin regulates active vitamin B6 levels and transcriptomic features of glioblastoma cell lines cultured under non-adherent, serum-free conditions.7
297241932018Chronophin regulates active vitamin B6 levels and transcriptomic features of glioblastoma cell lines cultured under non-adherent, serum-free conditions.7
263248842015Chronophin coordinates cell leading edge dynamics by controlling active cofilin levels.10
263248842015Chronophin coordinates cell leading edge dynamics by controlling active cofilin levels.10
232235682013A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation.12
232235682013A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation.12
185108742008Human brain pyridoxal-5'-phosphate phosphatase (PLPP):protein transduction of PEP-1-PLPP into PC12 cells.3
190008342008Chronophin mediates an ATP-sensing mechanism for cofilin dephosphorylation and neuronal cofilin-actin rod formation.58
185108742008Human brain pyridoxal-5'-phosphate phosphatase (PLPP):protein transduction of PEP-1-PLPP into PC12 cells.3
190008342008Chronophin mediates an ATP-sensing mechanism for cofilin dephosphorylation and neuronal cofilin-actin rod formation.58
155802682005Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics.145
163367862005Human brain pyridoxal-5'-phosphate phosphatase: production and characterization of monoclonal antibodies.0
155802682005Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics.145
163367862005Human brain pyridoxal-5'-phosphate phosphatase: production and characterization of monoclonal antibodies.0
145229542003Human pyridoxal phosphatase. Molecular cloning, functional expression, and tissue distribution.23

Citation

Dessen P

PDXP (pyridoxal phosphatase)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56303/pdxp-(pyridoxal-phosphatase)