Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 114836
MIM: 606446
HGNC: 21392
Ensembl: ENSG00000162739
Variants:
dbSNP: 114836
ClinVar: 114836
TCGA: ENSG00000162739
COSMIC: SLAMF6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000162739 | ENST00000368055 | Q96DU3 |
| ENSG00000162739 | ENST00000368057 | Q96DU3 |
| ENSG00000162739 | ENST00000368059 | Q96DU3 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Adaptive Immune System | REACTOME | R-HSA-1280218 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | REACTOME | R-HSA-198933 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38287061 | 2024 | Clinical and immunological relevance of SLAMF6 expression in the tumor microenvironment of breast cancer and melanoma. | 1 |
| 38287061 | 2024 | Clinical and immunological relevance of SLAMF6 expression in the tumor microenvironment of breast cancer and melanoma. | 1 |
| 35016729 | 2022 | SLAMF6 is associated with the susceptibility and severity of rheumatoid arthritis in the Chinese population. | 2 |
| 35016729 | 2022 | SLAMF6 is associated with the susceptibility and severity of rheumatoid arthritis in the Chinese population. | 2 |
| 33774556 | 2021 | Expression and function of SLAMF6 in CD8(+) T lymphocytes of patients with severe aplastic anemia. | 2 |
| 33774556 | 2021 | Expression and function of SLAMF6 in CD8(+) T lymphocytes of patients with severe aplastic anemia. | 2 |
| 31199820 | 2019 | SLAMF6 clustering is required to augment T cell activation. | 17 |
| 31199820 | 2019 | SLAMF6 clustering is required to augment T cell activation. | 17 |
| 29305520 | 2018 | Soluble SLAMF6 Receptor Induces Strong CD8(+) T-cell Effector Function and Improves Anti-Melanoma Activity In Vivo. | 12 |
| 29305520 | 2018 | Soluble SLAMF6 Receptor Induces Strong CD8(+) T-cell Effector Function and Improves Anti-Melanoma Activity In Vivo. | 12 |
| 28373584 | 2017 | Invariant NKT Cell Activation Is Potentiated by Homotypic trans-Ly108 Interactions. | 5 |
| 28546549 | 2017 | Restimulation-induced T-cell death through NTB-A/SAP signaling pathway is impaired in tuberculosis patients with depressed immune responses. | 4 |
| 28373584 | 2017 | Invariant NKT Cell Activation Is Potentiated by Homotypic trans-Ly108 Interactions. | 5 |
| 28546549 | 2017 | Restimulation-induced T-cell death through NTB-A/SAP signaling pathway is impaired in tuberculosis patients with depressed immune responses. | 4 |
| 26878112 | 2016 | A hematopoietic cell-driven mechanism involving SLAMF6 receptor, SAP adaptors and SHP-1 phosphatase regulates NK cell education. | 32 |
Citation
Dessen P
SLAMF6 (SLAM family member 6)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56305/slamf6-(slam-family-member-6)
