ZPR1 (ZPR1 zinc finger)

2016-10-01  

Identity

HGNC
LOCATION
11q23.3
LOCUSID
ALIAS
GKAF,ZNF259

Other Information

Locus ID:

NCBI: 8882
MIM: 603901
HGNC: 13051
Ensembl: ENSG00000109917

Variants:

dbSNP: 8882
ClinVar: 8882
TCGA: ENSG00000109917
COSMIC: ZPR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000109917ENST00000227322O75312
ENSG00000109917ENST00000425791F8WBC5
ENSG00000109917ENST00000429220H7C0E5
ENSG00000109917ENST00000431973H7BZS1
ENSG00000109917ENST00000444935H7BZM7
ENSG00000109917ENST00000449430H7C449

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
335675432021Implication between Genetic Variants from APOA5 and ZPR1 and NAFLD Severity in Patients with Hypertriglyceridemia.6
339863382021Kernel machine SNP set analysis finds the association of BUD13, ZPR1, and APOA5 variants with metabolic syndrome in Tehran Cardio-metabolic Genetics Study.10
335675432021Implication between Genetic Variants from APOA5 and ZPR1 and NAFLD Severity in Patients with Hypertriglyceridemia.6
339863382021Kernel machine SNP set analysis finds the association of BUD13, ZPR1, and APOA5 variants with metabolic syndrome in Tehran Cardio-metabolic Genetics Study.10
318282882020ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy.30
328076942020The ZPR1 genotype predicts myocardial infarction in patients with familial hypercholesterolemia.4
318282882020ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy.30
328076942020The ZPR1 genotype predicts myocardial infarction in patients with familial hypercholesterolemia.4
309027872019There is an association between a genetic polymorphism in the ZNF259 gene involved in lipid metabolism and coronary artery disease.4
309027872019There is an association between a genetic polymorphism in the ZNF259 gene involved in lipid metabolism and coronary artery disease.4
298510652018A ZPR1 mutation is associated with a novel syndrome of growth restriction, distinct craniofacial features, alopecia, and hypoplastic kidneys.4
298510652018A ZPR1 mutation is associated with a novel syndrome of growth restriction, distinct craniofacial features, alopecia, and hypoplastic kidneys.4
266346972016Multiple susceptibility loci at chromosome 11q23.3 are associated with plasma triglyceride in East Asians.20
274118542016Two-stage association study to identify the genetic susceptibility of a novel common variant of rs2075290 in ZPR1 to type 2 diabetes.29
266346972016Multiple susceptibility loci at chromosome 11q23.3 are associated with plasma triglyceride in East Asians.20

Citation

Dessen P

ZPR1 (ZPR1 zinc finger)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56312/zpr1-(zpr1-zinc-finger)