LPIN2 (lipin 2)

2016-10-01  

Identity

HGNC
LOCATION
18p11.31
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 9663
MIM: 605519
HGNC: 14450
Ensembl: ENSG00000101577

Variants:

dbSNP: 9663
ClinVar: 9663
TCGA: ENSG00000101577
COSMIC: LPIN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101577ENST00000261596Q92539
ENSG00000101577ENST00000584294J3KTK1
ENSG00000101577ENST00000584915J3QQN0

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Glycerolipid metabolismKEGGko00561
Glycerophospholipid metabolismKEGGko00564
Glycerolipid metabolismKEGGhsa00561
Glycerophospholipid metabolismKEGGhsa00564
Metabolic pathwaysKEGGhsa01100
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic ProphaseREACTOMER-HSA-68875
Nuclear Envelope BreakdownREACTOMER-HSA-2980766
Depolymerisation of the Nuclear LaminaREACTOMER-HSA-4419969
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Triglyceride BiosynthesisREACTOMER-HSA-75109
Phospholipid metabolismREACTOMER-HSA-1483257
Glycerophospholipid biosynthesisREACTOMER-HSA-1483206
Synthesis of PEREACTOMER-HSA-1483213
Synthesis of PCREACTOMER-HSA-1483191

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
378658622024LPIN2 -related Majeed syndrome: report of two Indian patients with novel variants in LPIN2 and review of literature.0
378658622024LPIN2 -related Majeed syndrome: report of two Indian patients with novel variants in LPIN2 and review of literature.0
379296252023Lipin-2 regulates the antiviral and anti-inflammatory responses to interferon.1
379296252023Lipin-2 regulates the antiviral and anti-inflammatory responses to interferon.1
333147772021Novel Majeed Syndrome-Causing LPIN2 Mutations Link Bone Inflammation to Inflammatory M2 Macrophages and Accelerated Osteoclastogenesis.7
335969342021Identification of lipidomic profiles associated with drug-resistant prostate cancer cells.11
333147772021Novel Majeed Syndrome-Causing LPIN2 Mutations Link Bone Inflammation to Inflammatory M2 Macrophages and Accelerated Osteoclastogenesis.7
335969342021Identification of lipidomic profiles associated with drug-resistant prostate cancer cells.11
317521562019Differential Roles of Lipin1 and Lipin2 in the Hepatitis C Virus Replication Cycle.3
317521562019Differential Roles of Lipin1 and Lipin2 in the Hepatitis C Virus Replication Cycle.3
283714102017New genes associated with rheumatoid arthritis identified by gene expression profiling.9
283714102017New genes associated with rheumatoid arthritis identified by gene expression profiling.9
230871832013Efficacy of anti-IL-1 treatment in Majeed syndrome.73
237925892013Chromosomal structural variations during progression of a prostate epithelial cell line to a malignant metastatic state inactivate the NF2, NIPSNAP1, UGT2B17, and LPIN2 genes.12
230871832013Efficacy of anti-IL-1 treatment in Majeed syndrome.73

Citation

Dessen P

LPIN2 (lipin 2)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56317/lpin2-(lipin-2)